(-)-象牙(洪达木)酮宁合成路线 （共 78 条）
反应条件
1: 95 percent / Nafion-H / toluene / 18 h / 20 °C 2: 97 percent / Me3S / methanol 3: 30 percent / LiAlH4 / tetrahydrofuran / 0.5 h / Heating 4: pyridine*SO3; Et3N / dimethylsulfoxide / 20 °C 5: TPAP; NMMO; 4 Angstroem mol. sieves / CH2Cl2 View Scheme
参考文献
Wee, Andrew G.H.; Yu, Qing
Tetrahedron Letters, 2000 , vol. 41, # 5 p. 587 - 590
反应条件
1: 95 percent / Nafion-H / toluene / 18 h / 20 °C 2: 97 percent / Me3S / methanol 3: 30 percent / LiAlH4 / tetrahydrofuran / 0.5 h / Heating 4: pyridine*SO3; Et3N / dimethylsulfoxide / 20 °C 5: TPAP; NMMO; 4 Angstroem mol. sieves / CH2Cl2 View Scheme
参考文献
Wee, Andrew G.H.; Yu, Qing
Tetrahedron Letters, 2000 , vol. 41, # 5 p. 587 - 590
反应条件
1: 73 percent / decahydronaphthalene / 2 h / 180 °C / Heating 2: 98 percent / NaOCH3 / methanol / 2 h / Heating 3: 90 percent / H2O; HCl / 0.5 h / 80 °C / Heating View Scheme
参考文献
Szabo; Sapi; Kalaus; et al.
Tetrahedron, 1983 , vol. 39, # 22 p. 3737 - 3747
反应条件
1: 72 percent / NaNO2 / H2O; acetic acid / 1 h / Ambient temperature 2: 46.5 percent / D-dibenzoyl tartaric acid/CH2Cl2 / ethanol 3: 73 percent / NaOH / ethanol; H2O / 1.5 h / Heating 4: 73 percent / decahydronaphthalene / 2 h / 180 °C / Heating 5: 98 percent / NaOCH3 / methanol / 2 h / Heating 6: 90 percent / H2O; HCl / 0.5 h / 80 °C / Heating View Scheme
参考文献
Szabo; Sapi; Kalaus; et al.
Tetrahedron, 1983 , vol. 39, # 22 p. 3737 - 3747
反应条件
1: 73 percent / NaOH / ethanol; H2O / 1.5 h / Heating 2: 73 percent / decahydronaphthalene / 2 h / 180 °C / Heating 3: 98 percent / NaOCH3 / methanol / 2 h / Heating 4: 90 percent / H2O; HCl / 0.5 h / 80 °C / Heating View Scheme
参考文献
Szabo; Sapi; Kalaus; et al.
Tetrahedron, 1983 , vol. 39, # 22 p. 3737 - 3747
反应条件
1: 46.5 percent / D-dibenzoyl tartaric acid/CH2Cl2 / ethanol 2: 73 percent / NaOH / ethanol; H2O / 1.5 h / Heating 3: 73 percent / decahydronaphthalene / 2 h / 180 °C / Heating 4: 98 percent / NaOCH3 / methanol / 2 h / Heating 5: 90 percent / H2O; HCl / 0.5 h / 80 °C / Heating View Scheme
参考文献
Szabo; Sapi; Kalaus; et al.
Tetrahedron, 1983 , vol. 39, # 22 p. 3737 - 3747
反应条件
1: 79 percent / KOH / ethanol; H2O / 4 h / Ambient temperature 2: 72 percent / NaNO2 / H2O; acetic acid / 1 h / Ambient temperature 3: 46.5 percent / D-dibenzoyl tartaric acid/CH2Cl2 / ethanol 4: 73 percent / NaOH / ethanol; H2O / 1.5 h / Heating 5: 73 percent / decahydronaphthalene / 2 h / 180 °C / Heating 6: 98 percent / NaOCH3 / methanol / 2 h / Heating 7: 90 percent / H2O; HCl / 0.5 h / 80 °C / Heating View Scheme
参考文献
Szabo; Sapi; Kalaus; et al.
Tetrahedron, 1983 , vol. 39, # 22 p. 3737 - 3747
反应条件
1: 98 percent / NaOCH3 / methanol / 2 h / Heating 2: 90 percent / H2O; HCl / 0.5 h / 80 °C / Heating View Scheme
参考文献
Szabo; Sapi; Kalaus; et al.
Tetrahedron, 1983 , vol. 39, # 22 p. 3737 - 3747
反应条件
1: 85 percent / sodium hydride / tetrahydrofuran / 1 h / Ambient temperature 2: 59 percent / tributyl-tin hydride, AIBN / toluene / 1.5 h / Heating View Scheme
参考文献
Hakam, Khalida; Thielmann, Marion; Thielmann, Thomas; Winterfeldt, Ekkehard
Tetrahedron, 1987 , vol. 43, # 9 p. 2035 - 2044
反应条件
trifluoroacetic acid 1 h; Heating;
参考文献
Lewin, G.; Poisson, J.; Toffoli, P.
Tetrahedron, 1987 , vol. 43, # 3 p. 493 - 500
