3,4-二氢-4-苯基-2(1H)-喹啉合成路线 （共 30 条）
反应条件
tri-ruthenium(0)dodecacarbonyl; tetra-(n-butyl)ammonium iodide in dimethyl sulfoxide; toluene
T=20 - 120°C; 20.08 h; Sealed tube; Overall yield = 58 percentSpectr.; regioselective reaction;
参考文献
Li, Bin; Park, Yoonsu; Chang, Sukbok
Journal of the American Chemical Society, 2014 , vol. 136, # 3 p. 1125 - 1131
反应条件
aluminum tri-bromide
T=25°C; 24 h;
参考文献
Koltunov, Konstantin Yu.; Prakash, G. K. Surya; Rasul, Golam; Olah, George A.
Heterocycles, 2004 , vol. 62, p. 757 - 772
反应条件
1.1: triethylamine / dichloromethane / 0.5 h / 20 °C / |Inert atmosphere
1.2: 10 h / 0 - 20 °C / |Inert atmosphere
2.1: AlCl3, aluminium chloride / 1,2-dichloro-benzene / 26 h / |Inert atmosphere; |Reflux
View Scheme
参考文献
Lee, Eun; Han, Seulaa; Jin, Guo Hua; Lee, Hwa Jin; Kim, Woo-Young; Ryu, Jae-Ha; Jeon, Raok
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 13 p. 3976 - 3978
反应条件
1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / water; toluene; ethanol / 24 h / |Reflux; |Inert atmosphere
2: tri-ruthenium(0)dodecacarbonyl / chlorobenzene; N,N-dimethyl acetamide / 20 - 120 °C / |Sealed tube
View Scheme
参考文献
Li, Bin; Park, Yoonsu; Chang, Sukbok
Journal of the American Chemical Society, 2014 , vol. 136, # 3 p. 1125 - 1131
反应条件
1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / water; toluene; ethanol / 24 h / |Reflux; |Inert atmosphere
2: tri-ruthenium(0)dodecacarbonyl / chlorobenzene; N,N-dimethyl acetamide / 20 - 120 °C / |Sealed tube
View Scheme
参考文献
Li, Bin; Park, Yoonsu; Chang, Sukbok
Journal of the American Chemical Society, 2014 , vol. 136, # 3 p. 1125 - 1131
反应条件
1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / water; toluene; ethanol / 24 h / |Reflux; |Inert atmosphere
2: tri-ruthenium(0)dodecacarbonyl; tetra-(n-butyl)ammonium iodide / toluene; dimethyl sulfoxide / 20.08 h / 20 - 120 °C / |Sealed tube
View Scheme
参考文献
Li, Bin; Park, Yoonsu; Chang, Sukbok
Journal of the American Chemical Society, 2014 , vol. 136, # 3 p. 1125 - 1131
反应条件
1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / water; toluene; ethanol / 24 h / |Reflux; |Inert atmosphere
2: tri-ruthenium(0)dodecacarbonyl; tetra-(n-butyl)ammonium iodide / toluene; dimethyl sulfoxide / 20.08 h / 20 - 120 °C / |Sealed tube
View Scheme
参考文献
Li, Bin; Park, Yoonsu; Chang, Sukbok
Journal of the American Chemical Society, 2014 , vol. 136, # 3 p. 1125 - 1131
反应条件
sodium amalgam; ethanol; water
参考文献
Stephenson
Journal of the Chemical Society, 1956 , p. 2557
参考文献
Knunjanz; Gambarjan
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1957 , p. 834,837; engl. Ausg. S. 855, 857
参考文献
Knunjanz; Gambarjan
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1957 , p. 834,837; engl. Ausg. S. 855, 857
