反应条件
1.1: N-chloro-succinimide / tetrachloromethane / 15 h / 20 °C
2.1: lithium diisopropyl amide / tetrahydrofuran / Inert atmosphere; Cooling
2.2: Inert atmosphere; Cooling
3.1: 1,1-dimethylethylmagnesium chloride / tetrahydrofuran / 0.17 h / -45 °C / Inert atmosphere
3.2: 1.7 h / -45 - 20 °C / Inert atmosphere
3.3: 1.5 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Fukuda, Shigehiko; Tsuji, Kazuhito; Musashi, Jun; Nonaka, Ryo; Kimura, Tsutomu; Satoh, Tsuyoshi
Synthesis, 2011 , # 22 art. no. F71511SS, p. 3615 - 3626
