4,9-二氢-3H-吡啶并(3,4-B)吲哚合成路线 (共 34 条)
反应条件
hydrogenchloride; zinc(II) chloride
1.) acetonitrile, 4 h, 50 deg C; 2.) 10 min; Yield given. Multistep reaction;
参考文献
Vacca, J. P.
Tetrahedron Letters, 1985 , vol. 26, # 10 p. 1277 - 1280
参考文献
Kardos; Blasko; Simonyi; Szantay
European Journal of Medicinal Chemistry, 1986 , vol. 21, # 2 p. 151 - 154
反应条件
1: 84 percent / benzene / 2 h
2: 60 percent / 2 N KOH / 24 h / Ambient temperature
View Scheme
参考文献
Akhrem, A. A.; Chernov, Yu. G.
Doklady Chemistry, 1983 , vol. 271, p. 247 - 248
Dokl. Akad. Nauk SSSR Ser. Khim., 1983 , vol. 271, # 4 p. 869 - 870
反应条件
in dichloromethane
20 h; Inert atmosphereReflux;
参考文献
Huan, Uozhen; Klin, Beata; Darras, Fouad H.; Heilmann, Joer; Decker, Michael
European Journal of Medicinal Chemistry, 2014 , vol. 81, p. 15 - 21