5-氯-1-甲基-4-硝基咪唑合成路线 （共 18 条）
参考文献
Bennett; Baker
Journal of the American Chemical Society, 1957 , vol. 79, p. 2188,2191
反应条件
bis-triphenylphosphine-palladium(II) chloride; tetrabutylammomium bromide; potassium carbonate in water
T=75 - 80°C; Suzuki coupling;
参考文献
Saadeh, Haythem A.; Mosleh, Ibrahim M.; El-Abadelah, Mustafa M.
Molecules, 2009 , vol. 14, # 8 p. 2758 - 2767
反应条件
potassium carbonate in acetone
Ambient temperature;
参考文献
Crawford, Duncan J. K.; Maddocks, John L.; Jones, D. Neville; Szawlowski, Paul
Journal of Medicinal Chemistry, 1996 , vol. 39, # 14 p. 2690 - 2695
反应条件
sodium hydride in N,N-dimethyl-formamide
1.) r.t., 10 min; 2.) 100 deg C, 1 h;
参考文献
Tennant, George; Wallis, Christopher J.; Weaver, George W.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 7 p. 817 - 825
反应条件
in water
T=22 - 25°C; 21 h;
参考文献
Mukherjee; Kumar; Seth; Bhaduri
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 5 p. 391 - 396
参考文献
Balaban
Journal of the Chemical Society, 1930 , p. 268,271
反应条件
potassium carbonate in acetone
Ambient temperature;
参考文献
Crawford, Duncan J. K.; Maddocks, John L.; Jones, D. Neville; Szawlowski, Paul
Journal of Medicinal Chemistry, 1996 , vol. 39, # 14 p. 2690 - 2695
反应条件
potassium carbonate
9 h; Heating;
参考文献
Mukherjee; Kumar; Seth; Bhaduri
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 5 p. 391 - 396
