1: 3-(4'-bromophenyl)propionic acid; diazomethyl-trimethyl-silane in methanol; diethyl ether; toluene T=20°C; 0.25 h; 2: 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl-4',4',5',5'-tetramethyl-1,3,2-dioxaborolane With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in dimethyl sulfoxide T=80°C; 2 h;

(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; 1-n-butyl-3-methylimidazolium tetrafluoroborate T=100°C; 2 h;

[1,3-bis(diphenylphosphino) propane] dichloronickel(II); 1,3-bis-(diphenylphosphino)propane; triethylamine in toluene T=100°C; 18 h; Inert atmosphere;

1.1: 78 percent / sodium hydrogensulfate; p-hydroquinone; 4-tert-butylcatechol / diethyl ether / 3 h / 200 °C 2.1: BMS / bis-(2-methoxy-ethyl) ether / 3.5 h / 0 - 140 °C 2.2: aq. NaOH; H2O2 / 3 h / 25 - 50 °C 3.1: CrO3; aq. H2SO4 / acetone / 0.5 h / 20 °C 4.1: 80 percent / thionyl chloride / 2 h / Heating 5.1: 88 percent / PdCl2(dppf); 1-butyl-3-methylimidazolium tetrafluoroborate; potassium acetate / 2 h / 100 °C View Scheme

1.1: BMS / bis-(2-methoxy-ethyl) ether / 3.5 h / 0 - 140 °C 1.2: aq. NaOH; H2O2 / 3 h / 25 - 50 °C 2.1: CrO3; aq. H2SO4 / acetone / 0.5 h / 20 °C 3.1: 80 percent / thionyl chloride / 2 h / Heating 4.1: 88 percent / PdCl2(dppf); 1-butyl-3-methylimidazolium tetrafluoroborate; potassium acetate / 2 h / 100 °C View Scheme

1: CrO3; aq. H2SO4 / acetone / 0.5 h / 20 °C 2: 80 percent / thionyl chloride / 2 h / Heating 3: 88 percent / PdCl2(dppf); 1-butyl-3-methylimidazolium tetrafluoroborate; potassium acetate / 2 h / 100 °C View Scheme

1.1: 76 percent / diethyl ether / 1 h / 20 °C 2.1: 78 percent / sodium hydrogensulfate; p-hydroquinone; 4-tert-butylcatechol / diethyl ether / 3 h / 200 °C 3.1: BMS / bis-(2-methoxy-ethyl) ether / 3.5 h / 0 - 140 °C 3.2: aq. NaOH; H2O2 / 3 h / 25 - 50 °C 4.1: CrO3; aq. H2SO4 / acetone / 0.5 h / 20 °C 5.1: 80 percent / thionyl chloride / 2 h / Heating 6.1: 88 percent / PdCl2(dppf); 1-butyl-3-methylimidazolium tetrafluoroborate; potassium acetate / 2 h / 100 °C View Scheme

1: 80 percent / thionyl chloride / 2 h / Heating 2: 88 percent / PdCl2(dppf); 1-butyl-3-methylimidazolium tetrafluoroborate; potassium acetate / 2 h / 100 °C View Scheme