N,N-二甲基甲酰胺二新戊基乙缩醛合成路线 （共 8 条）
反应条件
(i) SOCl2, (ii) /BRN= 1730984/, Na, CHCl3; Multistep reaction;
参考文献
Tsakotellis; Johnson; Skinner; Skidmore; Maibach
Journal of pharmaceutical sciences, 1971 , vol. 60, # 1 p. 84 - 89
参考文献
Brechbuehler,H. et al.
Helvetica Chimica Acta, 1965 , vol. 48, p. 1746 - 1771
Full Text Show Details
Costisella,B.; Gross,H.
Journal fuer Praktische Chemie (Leipzig), 1977 , vol. 319, p. 8 - 16
反应条件
in N,N-dimethyl-formamide T=150°C; 24 h;
参考文献
Nathubhai, Amit; Patterson, Richard; Woodman, Timothy J.; Sharp, Harriet E. C.; Chui, Miranda T. Y.; Chung, Hugo H. K.; Lau, Stephanie W. S.; Zheng, Jun; Lloyd, Matthew D.; Thompson, Andrew S.; Threadgill, Michael D.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 17 p. 6089 - 6099
反应条件
in N,N-dimethyl-formamide 1 h; Heating;
参考文献
Tisler, Miha; Stanovnik, Branko; Zrimsek, Zdenka
Heterocycles, 1982 , vol. 17, p. 405 - 411
参考文献
Brechbuehler,H. et al.
Helvetica Chimica Acta, 1965 , vol. 48, p. 1746 - 1771
反应条件
in N,N-dimethyl-formamide
T=150°C; 24 h;
参考文献
Nathubhai, Amit; Patterson, Richard; Woodman, Timothy J.; Sharp, Harriet E. C.; Chui, Miranda T. Y.; Chung, Hugo H. K.; Lau, Stephanie W. S.; Zheng, Jun; Lloyd, Matthew D.; Thompson, Andrew S.; Threadgill, Michael D.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 17 p. 6089 - 6099
反应条件
in N-methyl-acetamide; hexane; ethyl acetate; isopropyl alcohol
参考文献
Hoffmann-La Roche Inc.
Patent: US4169201 A1, 1979 ;
反应条件
in N,N-dimethyl-formamide
T=130 - 135°C;
参考文献
Xia, Zhiqiang; Przewloka, Teresa; Koya, Keizo; Ono, Mitsunori; Chen, Shoujun; Sun, Lijun
Tetrahedron Letters, 2006 , vol. 47, # 50 p. 8817 - 8820
