3-甲基-6-(1-甲基乙亚基)环己-2-烯-1-酮合成路线 （共 58 条）
反应条件
cyclohexyl(triphenyl)phosphonium bromide; hydrogen; [{Rh(μ-Cl)(1,5-cyclooctadiene)}2]; (S)-(−)-XylBINAP in tetrahydrofuran T=50°C; P=22502.3 Torr; 18 h;
参考文献
Takasago International Corporation
Patent: US6342644 B1, 2002 ;
Location in patent: Example 5 ;
反应条件
(R)-DTBM-Segphos; [Cu(PPh3)2NO3]; hydrogen; sodium t-butanolate in isopropyl alcohol T=50°C; P=37503.8 Torr; 18 h; optical yield given as percent eeenantioselective reaction;
参考文献
Shimizu, Hideo; Nagano, Takuto; Sayo, Noboru; Saito, Takao; Ohshima, Takashi; Mashima, Kazushi
Synlett, 2009 , # 19 p. 3143 - 3146
反应条件
[RhI{(S)-tol-binap}]2; hydrogen in dichloromethane T=50°C; P=22067.3 Torr; 18 h; Autoclave; optical yield given as percent ee;
参考文献
Ohshima, Takashi; Tadaoka, Hiroshi; Hori, Kiyoto; Sayo, Noboru; Mashima, Kazushi
Chemistry - A European Journal, 2008 , vol. 14, # 7 p. 2060 - 2066
反应条件
[RhCl{(S)-segphos}]2; hydrogen in dichloromethane T=50°C; P=22067.3 Torr; 18 h; Autoclave;
参考文献
Ohshima, Takashi; Tadaoka, Hiroshi; Hori, Kiyoto; Sayo, Noboru; Mashima, Kazushi
Chemistry - A European Journal, 2008 , vol. 14, # 7 p. 2060 - 2066
反应条件
hydrogen; HRuCl(TBPC)2 in toluene T=60°C; P=7600 Torr; 24 h;
参考文献
Le Maux, Paul; Massonneau, Viviane; Simonneaux, Gerard
Tetrahedron, 1988 , vol. 44, # 5 p. 1409 - 1412
反应条件
hydrogen; HRuCl(TBPC)2 in toluene T=65°C; P=7600 Torr; 26 h; asymmetric synthesis, var. chiral ruthenium catalyst, variation of time; MechanismProduct distribution;
参考文献
Le Maux, Paul; Massonneau, Viviane; Simonneaux, Gerard
Tetrahedron, 1988 , vol. 44, # 5 p. 1409 - 1412
反应条件
cyclohexyl(triphenyl)phosphonium bromide; hydrogen; [{Rh(μ-Cl)(1,5-cyclooctadiene)}2]; (S)-(−)-XylBINAP in tetrahydrofuran T=50°C; P=22502.3 Torr; 18 h;
参考文献
Takasago International Corporation
Patent: US6342644 B1, 2002 ;
Location in patent: Example 5 ;
反应条件
[RhI{(S)-segphos}]2; hydrogen in dichloromethane T=50°C; P=22067.3 Torr; 18 h; Autoclave;
参考文献
Ohshima, Takashi; Tadaoka, Hiroshi; Hori, Kiyoto; Sayo, Noboru; Mashima, Kazushi
Chemistry - A European Journal, 2008 , vol. 14, # 7 p. 2060 - 2066
反应条件
[RhCl{(S)-segphos}]2; hydrogen in dichloromethane T=50°C; P=22067.3 Torr; 18 h; Autoclave;
参考文献
Ohshima, Takashi; Tadaoka, Hiroshi; Hori, Kiyoto; Sayo, Noboru; Mashima, Kazushi
Chemistry - A European Journal, 2008 , vol. 14, # 7 p. 2060 - 2066
反应条件
hydrogen; HRuCl(TBPC)2 in toluene T=65°C; P=7600 Torr; 26 h; asymmetric synthesis, var. chiral ruthenium catalyst, variation of time; MechanismProduct distribution;
参考文献
Le Maux, Paul; Massonneau, Viviane; Simonneaux, Gerard
Tetrahedron, 1988 , vol. 44, # 5 p. 1409 - 1412
