4-甲基-4-戊烯酸乙酯合成路线 （共 22 条）
反应条件
palladium dichloride T=100°C; 24 h;
参考文献
Hosaka,S.; Tsuji,J.
Tetrahedron, 1971 , vol. 27, p. 3821 - 3829
参考文献
Haas, Juergen; Piguel, Sandrine; Wirth, Thomas
Organic Letters, 2002 , vol. 4, # 2 p. 297 - 300
反应条件
(i) PdCl2, (ii) /BRN= 3587209/, EtOH; Multistep reaction. Further byproducts given;
参考文献
Tsuji,J.; Hosaka,S.
Journal of the American Chemical Society, 1965 , vol. 87, p. 4075 - 4079
反应条件
molybdenium(VI) dioxodichloride 1) THF, -70 degC, 2 h; 2) THF; Yield given. Multistep reaction;
参考文献
Kauffmann, Thomas; Enk, Manfred; Kaschube, Wilfried; Toliopoulos, Euripides; Wingbermuehle, Dorothea
Angewandte Chemie, 1986 , vol. 98, # 10 p. 928 - 929
反应条件
sodium ethanolate; sodium iodide 1.) EtOH, room temp., overnight; 2.) DMF, reflux, 16 h; Yield given. Multistep reaction;
参考文献
Breuilles, Pascal; Uguen, Daniel
Bulletin de la Societe Chimique de France, 1988 , # 4 p. 705 - 720
参考文献
Jones; Tattersall
Journal of the Chemical Society, 1904 , vol. 85, p. 1693
反应条件
sodium hydroxide in ethanol
2 h; Heating;
参考文献
Braddock, D. Christopher; Cansell, Gemma; Hermitage, Stephen A.
Chemical Communications, 2006 , # 23 p. 2483 - 2485
反应条件
1: 87 percent / LiAlH4 / diethyl ether / 2 h / Heating
2: pyridine / 3 h / 0 °C
View Scheme
参考文献
Scholte, Andrew A.; Eubanks, Lisa M.; Poulter, C. Dale; Vederas, John C.
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 4 p. 763 - 770
反应条件
1: NaOH / ethanol / Heating
2: (COCl)2
3: HCl / diethyl ether
4: diethyl ether
View Scheme
参考文献
Grob,C.A.; Waldner,A.
Helvetica Chimica Acta, 1979 , vol. 62, p. 1854 - 1865
反应条件
1: LiAlH4 / tetrahydrofuran / 1 h / 0 °C
2: 69 percent / PPh3, imidazole, I2 / benzene / 1 h / Ambient temperature
View Scheme
参考文献
Kocienski, Philip J.; Love, Christopher J.; Whitby, Richard J.; Costello, Gerard; Roberts, David A.
Tetrahedron, 1989 , vol. 45, # 12 p. 3839 - 3848
