N4-(4-氟苄基)-1,2,4-苯三胺合成路线 （共 5 条）
反应条件
hydrogen; 1 Pd/C in 1,4-dioxane T=20 - 50°C; 168 h;
参考文献
WO2011/12659 A2, ;
Page/Page column 17 ;
反应条件
hydrogen in methanol T=20°C; P=760.051 Torr; 3 h;
参考文献
Acta Pharmacologica Sinica, , vol. 34, # 10 p. 1359 - 1366
反应条件
1: toluene-4-sulfonic acid / toluene / 3 h / |Reflux 2: sodium tetrahydroborate / 1,4-dioxane; methanol / 2 h / 20 °C 3: hydrogen / methanol / 3 h / 20 °C / 760.05 Torr View Scheme
参考文献
Acta Pharmacologica Sinica, , vol. 34, # 10 p. 1359 - 1366
反应条件
1: toluene-4-sulfonic acid / toluene / 3 h / |Reflux 2: sodium tetrahydroborate / 1,4-dioxane; methanol / 2 h / 20 °C 3: hydrogen / methanol / 3 h / 20 °C / 760.05 Torr View Scheme
参考文献
Acta Pharmacologica Sinica, , vol. 34, # 10 p. 1359 - 1366
反应条件
1: sodium tetrahydroborate / 1,4-dioxane; methanol / 2 h / 20 °C 2: hydrogen / methanol / 3 h / 20 °C / 760.05 Torr View Scheme
参考文献
Acta Pharmacologica Sinica, , vol. 34, # 10 p. 1359 - 1366
