3-氨基-5-苯基-1,2,4-三唑合成路线 （共 6 条）
参考文献
Dolzhenko, Anton V.; Dolzhenko, Anna V.; Chui, Wai-Keung
Tetrahedron, 2007 , vol. 63, # 52 p. 12888 - 12895
反应条件
1: aq. NaOH 2: 220 °C View Scheme
参考文献
Bera, Hriday; Tan, Bee Jen; Sun, Lingyi; Dolzhenko, Anton V.; Chui, Wai-Keung; Chiu, Gigi Nagar Chee
European Journal of Medicinal Chemistry, 2013 , vol. 67, p. 325 - 334
反应条件
1: sodium hydroxide / 0.33 h / 180 °C 2: water / 180 °C / |Microwave irradiation View Scheme
参考文献
Bera, Hriday; Tan, Bee Jen; Sun, Lingyi; Dolzhenko, Anton V.; Chui, Wai-Keung; Chiu, Gigi Nagar Chee
European Journal of Medicinal Chemistry, 2013 , vol. 67, p. 325 - 334
反应条件
hydrogenchloride in ethanol; water Reflux;
参考文献
Chernyshev; Tarasova; Chernysheva; Taranushich
Russian Journal of Applied Chemistry, 2011 , vol. 84, # 11 p. 1890 - 1896
反应条件
1: conc. nitric acid, NaNO2 / H2O / 0.75 h / 0 - 5 °C
2: CH2Cl2 / -40 °C / few minutes
3: benzyltriethylammonium permanganate / CH2Cl2 / 0.25 h / 0 - 5 °C
View Scheme
参考文献
Ege, Guenter; Heck, Reinhard; Gilbert, Karlheinz; Irngartinger, Hermann; Huber-Patz, Ursula; Rodewald, Hans
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1629 - 1639
反应条件
nitric acid; sodium nitrite in water
T=0°C;
参考文献
Ege, Guenter; Heck, Reinhard; Gilbert, Karlheinz; Irngartinger, Hermann; Huber-Patz, Ursula; Rodewald, Hans
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1629 - 1639
