2-溴-4-甲基吡啶合成路线

4926-28-72-溴-4-甲基吡啶

26156-48-92-溴吡啶-4-甲酸甲酯

参考文献

PFIZER INC.; BAGLEY, Scott William; GRIFFITH, David Andrew; KUNG, Daniel Wei-Shung
Patent: WO2011/58473 A1, 2011 ;

4926-28-72-溴-4-甲基吡啶

1620-76-42-氰基-4-甲基吡啶

参考文献

Case; Kasper
Journal of the American Chemical Society, 1956 , vol. 78, p. 5842

4926-28-72-溴-4-甲基吡啶+

1461-22-9三丁基氯化锡

301652-23-34-甲基-2-(三正丁基锡)吡啶

参考文献

Nierengarten, Helene; Rojo, Javier; Leize, Emmanuelle; Lehn, Jean-Marie; Van Dorsselaer, Alain
European Journal of Inorganic Chemistry, 2002 , # 3 p. 573 - 579

4926-28-72-溴-4-甲基吡啶+

1066-54-2三甲基乙炔基硅

656800-40-72-甲基-6-((三甲基锡)乙炔)吡啶

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/13135 A1, 2004 ;
Location in patent: Page 43 ;
WO 2004/013135 A1

4926-28-72-溴-4-甲基吡啶+

17933-03-83-甲基苯硼酸

80635-91-24-甲基-2-间甲苯基吡啶

参考文献

Jung, Sungouk; Kang, Youngjin; Kim, Hyung-Sun; Kim, Yun-Hi; Lee, Chang-Lyoul; Kim, Jang-Joo; Lee, Sung-Koo; Kwon, Soon-Ki
European Journal of Inorganic Chemistry, 2004 , # 17 p. 3415 - 3423

4926-28-72-溴-4-甲基吡啶+

5720-05-84-甲基苯硼酸

80635-92-34-甲基-2-对甲苯基吡啶

参考文献

Gellibert, Francoise; De Gouville, Anne-Charlotte; Woolven, James; Mathews, Neil; Nguyen, Van-Loc; Bertho-Ruault, Cecile; Patikis, Angela; Grygielko, Eugene T.; Laping, Nicholas J.; Huet, Stephane
Journal of Medicinal Chemistry, 2006 , vol. 49, # 7 p. 2210 - 2221

4926-28-72-溴-4-甲基吡啶+

16152-51-54-异丙基苯基硼酸

80635-97-82-(4-异丙基苯基)-4-甲基吡啶

参考文献

Gellibert, Francoise; De Gouville, Anne-Charlotte; Woolven, James; Mathews, Neil; Nguyen, Van-Loc; Bertho-Ruault, Cecile; Patikis, Angela; Grygielko, Eugene T.; Laping, Nicholas J.; Huet, Stephane
Journal of Medicinal Chemistry, 2006 , vol. 49, # 7 p. 2210 - 2221

4926-28-72-溴-4-甲基吡啶+

13139-86-13-甲基-CBS-氧硼啶

80636-01-72-(4-甲氧基苯基)-4-甲基吡啶

参考文献

Filosa, Rosanna; Peduto, Antonella; de Caprariis, Paolo; Saturnino, Carmela; Festa, Michela; Petrella, Antonello; Pau, Amedeo; Pinna, Gerard Aime; La Colla, Paolo; Busonera, Bernardetta; Loddo, Roberta
European Journal of Medicinal Chemistry, 2007 , vol. 42, # 3 p. 293 - 306

4926-28-72-溴-4-甲基吡啶+

14221-01-3四三苯基膦钯+

5720-07-04-甲氧基苯硼酸

80636-01-72-(4-甲氧基苯基)-4-甲基吡啶

参考文献

Fujisawa Pharmaceutical Co., Ltd.
Patent: US6521643 B1, 2003 ;

4926-28-72-溴-4-甲基吡啶+

5720-07-04-甲氧基苯硼酸

80636-01-72-(4-甲氧基苯基)-4-甲基吡啶

参考文献

Au, Vonika Ka-Man; Wong, Keith Man-Chung; Zhu, Nianyong; Yam, Vivian Wing-Wah
Chemistry - A European Journal, 2011 , vol. 17, # 1 p. 130 - 142