2-溴-4-甲基吡啶合成路线

4926-28-72-溴-4-甲基吡啶

83004-14-22-溴-4-(溴甲基)吡啶

参考文献

Zeneca Limited; Zeneca Pharma S. A.
Patent: US6362336 B1, 2002 ;
Location in patent: Example 59 ;
US 6362336 B1

4926-28-72-溴-4-甲基吡啶+

34241-39-9

83004-14-22-溴-4-(溴甲基)吡啶

参考文献

Zeneca Limited; Zeneca Pharma S.A.,
Patent: US5962458 A1, 1999 ;
US 5962458 A

4926-28-72-溴-4-甲基吡啶

935861-30-62-(4-甲氧基苯基)异烟酸

参考文献

Filosa, Rosanna; Peduto, Antonella; de Caprariis, Paolo; Saturnino, Carmela; Festa, Michela; Petrella, Antonello; Pau, Amedeo; Pinna, Gerard Aime; La Colla, Paolo; Busonera, Bernardetta; Loddo, Roberta
European Journal of Medicinal Chemistry, 2007 , vol. 42, # 3 p. 293 - 306

4926-28-72-溴-4-甲基吡啶

446880-81-52-溴-4-[3-(2-吡啶)-1H-吡唑-4-基]吡啶

参考文献

Ciayadi, Rudy; Potdar, Mahesh; Walton, Kelly L.; Harrison, Craig A.; Kelso, Geoffrey F.; Harris, Simon J.; Hearn, Milton T.W.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5642 - 5645

4926-28-72-溴-4-甲基吡啶+

128796-39-44-三氟甲基苯硼酸

452342-99-34-甲基-2-(4-(三氟甲基)苯基)吡啶

参考文献

Gellibert, Francoise; De Gouville, Anne-Charlotte; Woolven, James; Mathews, Neil; Nguyen, Van-Loc; Bertho-Ruault, Cecile; Patikis, Angela; Grygielko, Eugene T.; Laping, Nicholas J.; Huet, Stephane
Journal of Medicinal Chemistry, 2006 , vol. 49, # 7 p. 2210 - 2221

4926-28-72-溴-4-甲基吡啶

452343-16-7

参考文献

Gellibert, Francoise; De Gouville, Anne-Charlotte; Woolven, James; Mathews, Neil; Nguyen, Van-Loc; Bertho-Ruault, Cecile; Patikis, Angela; Grygielko, Eugene T.; Laping, Nicholas J.; Huet, Stephane
Journal of Medicinal Chemistry, 2006 , vol. 49, # 7 p. 2210 - 2221

4926-28-72-溴-4-甲基吡啶+

2524-52-92-吡啶甲酸乙酯

446852-65-92-(2-溴吡啶-4-基)-1-(吡啶-2-基)乙酮

参考文献

Ciayadi, Rudy; Potdar, Mahesh; Walton, Kelly L.; Harrison, Craig A.; Kelso, Geoffrey F.; Harris, Simon J.; Hearn, Milton T.W.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5642 - 5645

4926-28-72-溴-4-甲基吡啶+

13602-11-46-甲基-2-吡啶甲酸甲酯

446880-80-42-(2-溴-4-吡啶)-1-(6-甲基-2-吡啶)乙酮

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/13138 A2, 2004 ;
Location in patent: Page 26 ;
WO 2004/013138 A2

4926-28-72-溴-4-甲基吡啶+

29681-38-75-甲基吡啶-2-羧酸甲酯

446880-80-42-(2-溴-4-吡啶)-1-(6-甲基-2-吡啶)乙酮

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/13134 A2, 2004 ;
Location in patent: Page 33 ;
WO 2004/013134 A2

4926-28-72-溴-4-甲基吡啶+

39640-51-2乙基 6-甲基吡啶-2-羧酸酯

446880-80-42-(2-溴-4-吡啶)-1-(6-甲基-2-吡啶)乙酮

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/13135 A1, 2004 ;
Location in patent: Page 54 ;
WO 2004/013135 A1