3,4-二氢-1H-苯并吡喃合成路线 （共 99 条）
反应条件
T=413°C; P=170 Torr; 4.5 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Paul, Gitendra C.; Gajewski, Joseph J.
Journal of Organic Chemistry, 1993 , vol. 58, # 19 p. 5060 - 5062
反应条件
T=413°C; P=135 Torr; 4.5 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Paul, Gitendra C.; Gajewski, Joseph J.
Journal of Organic Chemistry, 1993 , vol. 58, # 19 p. 5060 - 5062
反应条件
T=413°C; P=1 - 1.5 Torr; 4.5 h; other pressure; also in the presence of H2 or cis- and trans-2-butene; Product distributionMechanism;
参考文献
Paul, Gitendra C.; Gajewski, Joseph J.
Journal of Organic Chemistry, 1993 , vol. 58, # 19 p. 5060 - 5062
反应条件
in toluene T=609.9°C; MechanismKinetics;
参考文献
Dorrestijn, Edwin; Pugin, Raphael; Nogales, M. Victoria Ciriano; Mulder, Peter
Journal of Organic Chemistry, 1997 , vol. 62, # 14 p. 4804 - 4810
反应条件
carbon disulfide; aluminium trichloride
参考文献
Daukshas, V. K.; Gaidyalis, P. G.; Udrenaite, E. B.; Pyatrauskas, O. Yu.; Brukshtus, A. B.
Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 9 p. 611 - 614
Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 9 p. 1069 - 1071
反应条件
aluminium trichloride in dichloromethane T=15°C; 1 h;
参考文献
Daukshas, V. K.; Gaidyalis, P. G.; Udrenaite, E. B.; Pyatrauskas, O. Yu.; Brukshtus, A. B.
Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 9 p. 611 - 614
Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 9 p. 1069 - 1071
反应条件
potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in N,N-dimethyl-formamide T=95°C; 5 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GmbH
Patent: WO2009/62289 A1, 2009 ;
Location in patent: Page/Page column 79; 80 ;
反应条件
n-butyllithium in tetrahydrofuran; N-methyl-acetamide
参考文献
Rhone-Poulenc Rorer, S.A.
Patent: US5936097 A1, 1999 ;
US 5936097 A
反应条件
1: 3,4-dihydro-2H-1-benzopyran With n-butyllithium in diethyl ether; hexane T=20°C; 2.66667 h; Heating / reflux; 2: carbon dioxide in diethyl ether; hexane T=20°C;
参考文献
Actelion Phamaceuticals Ltd.
Patent: US2010/16401 A1, 2010 ;
Location in patent: Page/Page column 39 ;
反应条件
hydrogen in toluene T=629.9°C; other temperature 760-1110 K; MechanismKineticsRate constant;
参考文献
Dorrestijn, Edwin; Pugin, Raphael; Nogales, M. Victoria Ciriano; Mulder, Peter
Journal of Organic Chemistry, 1997 , vol. 62, # 14 p. 4804 - 4810
