3,4-二氢-1H-苯并吡喃合成路线 （共 99 条）
反应条件
1: 50 percent / baker's yeast; aq. D-glucose / ethanol / 48 h / 35 - 38 °C
2: LiAlH4 / diethyl ether / 5 h / Heating
3: pyridine / 0 °C
4: aq. NaOH / propan-2-ol / 5 h / 70 - 80 °C
View Scheme
参考文献
Brenna, Elisabetta; Fronza, Giovanni; Fuganti, Claudio; Gatti, Francesco G.; Grande, Valentina; Serra, Stefano; Guillou, Claude; Reniero, Fabiano; Serra, Francesca
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 24 p. 9383 - 9388
反应条件
1: 85 percent / tetrabutylammonium chloride; sodium bicarbonate; palladium acetate / dimethylformamide / 22 h / 45 °C
2: 98 percent / sodium borohydride / methanol / 20 °C
3: 87 percent / Pd(OAc)2; Cs2CO3; 2-(di-tert-butylphosphanyl)-1,1'-binaphthyl / toluene / 21 h / 65 °C
View Scheme
参考文献
Toracca, Karen E.; Kuwabe, Shin-Itsu; Buchwald, Stephen L.
Journal of the American Chemical Society, 2000 , vol. 122, # 51 p. 12907 - 12908
反应条件
1: 98 percent / sodium borohydride / methanol / 20 °C
2: 87 percent / Pd(OAc)2; Cs2CO3; 2-(di-tert-butylphosphanyl)-1,1'-binaphthyl / toluene / 21 h / 65 °C
View Scheme
参考文献
Toracca, Karen E.; Kuwabe, Shin-Itsu; Buchwald, Stephen L.
Journal of the American Chemical Society, 2000 , vol. 122, # 51 p. 12907 - 12908
反应条件
triethylamine in dichloromethane
Ambient temperature;
参考文献
Procopiou, Panayiotis A.; Brodie, Alastair C.; Deal, Martyn J.; Hayman, David F.
Tetrahedron Letters, 1993 , vol. 34, # 46 p. 7483 - 7486
反应条件
1: 71 percent / diethyl ether / 0 - 20 °C
2: 87 percent / Pd(OAc)2; Cs2CO3; 2-(di-tert-butylphosphanyl)-1,1'-binaphthyl / toluene / 21 h / 65 °C
View Scheme
参考文献
Toracca, Karen E.; Kuwabe, Shin-Itsu; Buchwald, Stephen L.
Journal of the American Chemical Society, 2000 , vol. 122, # 51 p. 12907 - 12908
反应条件
1: 51 percent / pyridinium chlorochromate / CH2Cl2 / 1.5 h / 20 °C
2: 71 percent / diethyl ether / 0 - 20 °C
3: 87 percent / Pd(OAc)2; Cs2CO3; 2-(di-tert-butylphosphanyl)-1,1'-binaphthyl / toluene / 21 h / 65 °C
View Scheme
参考文献
Toracca, Karen E.; Kuwabe, Shin-Itsu; Buchwald, Stephen L.
Journal of the American Chemical Society, 2000 , vol. 122, # 51 p. 12907 - 12908
反应条件
1,3-Diiodo-5,5-dimethyl-2,4-imidazolidinedione in ethyl acetate
T=40°C; 9 h; Irradiation;
参考文献
Furuyama, Shusuke; Togo, Hideo
Synlett, 2010 , # 15 p. 2325 - 2329
反应条件
iodine; mercury(II) oxide in tetrachloromethane
1 h; Heating;
参考文献
O'Dell, Dale E.; Loper, John T.; Macdonald, Timothy L.
Journal of Organic Chemistry, 1988 , vol. 53, # 22 p. 5225 - 5229
反应条件
(η5-ethyltetramethylcyclopentadienyl)(η6-benzene)rhodium(III) hexafluorophosphate
1.) acetone, nitromethane, 80 deg C, 4 d, 2.) dimethyl sulphoxide, 1 h, heating; Yield given. Multistep reaction;
参考文献
Houghton, Roy P.; Voyle, Martyn; Price, Raymond
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 5 p. 925 - 931
反应条件
1: sodium ethylate; alcohol
2: zinc chloride
View Scheme
参考文献
Rindfusz
Journal of the American Chemical Society, 1919 , vol. 41, p. 669
