5-溴-2-(四氢吡喃-4-氧基)吡啶合成路线 （共 2 条）
反应条件
1: 2,5-dibromo-pyridine With sodium hydride in DMF (N,N-dimethyl-formamide) 2: 4-hydroxypyran in DMF (N,N-dimethyl-formamide) T=0 - 20°C; 24 h;
参考文献
WO2005/90300 A1, ;
Page/Page column 38 ;
WO 2005/090300 A1
反应条件
1: 4-hydroxytetrahydro-4H-pyran With sodium hydride in N,N-dimethyl-formamide T=0 - 20°C; 0.75 h; 2: 5-Bromo-2-chloropyridine in N,N-dimethyl-formamide T=60°C;
参考文献
US2014/121200 A1, ;
Paragraph 0222; 0223 ;
