2-(4-(叔丁氧基羰基氨基)苯基)噻唑-4-羧酸乙酯合成路线 (共 2 条)
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether; water
T=80°C; 20 h;
参考文献
Boehringer Ingelheim (Canada) Ltd.
Patent: US2003/236251 A1, 2003 ;
Location in patent: Page 27-28 ;
反应条件
in tetrahydrofuran
36 h; Heating / reflux;
参考文献
SPIROGEN LIMITED
Patent: WO2005/85177 A2, 2005 ;
Location in patent: Page/Page column 39-41 ;