1-苯基-2-丁烯-1-酮合成路线 （共 117 条）
反应条件
[HMim][p-TSA]
T=60°C; Michael addition; 48 h; neat (no solvent);
参考文献
Han, Feng; Yang, Lei; Li, Zhen; Xia, Chungu
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 2 p. 346 - 354
反应条件
boron tribromide; ethylene glycol in dichloromethane
T=0°C; 0.5 h; Inert atmosphere;
参考文献
Lee, Adam Shih-Yuan; Wang, Shu-Huei; Chang, Yu-Ting
Journal of the Chinese Chemical Society, 2014 , vol. 61, # 3 p. 364 - 368
反应条件
oxygen
T=130°C; 2 h; Yield given;
参考文献
Wendelin, Winfried; Schermanz, Karl
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 1 p. 65 - 69
反应条件
1: 74 percent / EtONa / ethanol / 18 h / Ambient temperature
2: 6 N aq. HCl / 18 h / Heating
3: H2SO4 conc. / 3 h / Heating
4: 55 percent / parachloranile / xylene / 16 h / Heating
View Scheme
参考文献
Lakhlifi, Tahar; Sedqui, Ahmed; Fathi, Toufik; Laude, Bernard; Robert, Jean-Francois
Canadian Journal of Chemistry, 1994 , vol. 72, # 6 p. 1417 - 1423
反应条件
1: 69 percent / 1.) -23 deg C, 5.25 h, 2.) room temperature, 45 min
2: 75 percent / Raney nickel / ethanol / 20 h / 90 °C
View Scheme
参考文献
Fleming, Ian; Henning, Rolf; Parker, David C.; Plaut, Howard E.; Sanderson, Philip E. J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 4 p. 317 - 338
反应条件
1: 69 percent / 1.) -23 deg C, 5.25 h, 2.) room temperature, 45 min
2: 75 percent / Raney nickel / ethanol / 20 h / 90 °C
3: 88 percent / HBF4*Et2O / CH2Cl2 / 1 h / Ambient temperature
View Scheme
参考文献
Fleming, Ian; Henning, Rolf; Parker, David C.; Plaut, Howard E.; Sanderson, Philip E. J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 4 p. 317 - 338
反应条件
n-butyllithium; C31H35N2O5(1+)*Cl(1-); lithium chloride in hexane; toluene
T=20°C; Michael Addition; 24 h; Inert atmosphere; chemoselective reaction;
参考文献
Song, Jing-Ru; Huang, Zhi-Tang; Zheng, Qi-Yu
Tetrahedron, 2013 , vol. 69, # 35 p. 7308 - 7313
