1-苯基-2-丁烯-1-酮合成路线 （共 117 条）
反应条件
1: 81 percent / PdCl2(MeCN)2, triethylamine / acetonitrile / 12 h / Heating 2: 1.) CuI / 1.) ether, RT, 15 min; 2.) ether, RT, overnight View Scheme
参考文献
Murahashi, Shun-Ichi; Mitsue, Yo; Tsumiyama, Tatsuo
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 9 p. 3285 - 3290
反应条件
1: 1.) (CH3)2SO4, 2.) 10percent K2CO3 / 1.) ethyl acetate, reflux, 2 h, 2.) benzene, 80 deg C, 2 h 2: p-TsOH / benzene / 2 h / Heating View Scheme
参考文献
Hayakawa, Satoshi; Michiue, Tohru; Okamoto, Masao; Hatakeyama, Shoko; Ohta, Shunsaku
Heterocycles, 1988 , vol. 27, # 2 p. 457 - 474
反应条件
1: I2, Mg / 1.) THF, 0 deg C, 2.) THF, 0 deg C, 30 min 2: 1.) (CH3)2SO4, 2.) 10percent K2CO3 / 1.) ethyl acetate, reflux, 2 h, 2.) benzene, 80 deg C, 2 h 3: p-TsOH / benzene / 2 h / Heating View Scheme
参考文献
Hayakawa, Satoshi; Michiue, Tohru; Okamoto, Masao; Hatakeyama, Shoko; Ohta, Shunsaku
Heterocycles, 1988 , vol. 27, # 2 p. 457 - 474
反应条件
toluene-4-sulfonic acid in benzene 12 h;
参考文献
Fleming, Ian; Floyd, Christopher D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 969 - 976
反应条件
toluene-4-sulfonic acid in benzene 12 h;
参考文献
Fleming, Ian; Floyd, Christopher D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 969 - 976
反应条件
1.1: t-BuOK; BuLi / hexane; tetrahydrofuran / 2 h / -95 °C 1.2: ClSnBu3 / hexane; tetrahydrofuran / 2 h / -95 - -50 °C 1.3: 0.10 g / LiCl; CuCl / Pd(PPh3)4 / dimethylsulfoxide / 2 h / 25 °C 2.1: 74 percent / Amberlyst-15 / CH2Cl2 / 1 h / 25 °C View Scheme
参考文献
Tivola, Paolo Balma; Deagostino, Anna; Prandi, Cristina; Venturello, Paolo
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 4 p. 437 - 441
反应条件
1: tetrahydrofuran 2: 1.) lithium / 1.) ether, overnight, 2.) 2 h, room temperature 3: 80 percent / methyl lithium / diethyl ether; tetrahydrofuran / 2 h / 0 °C 4: toluene-p-sulphonic acid / benzene / 12 h View Scheme
参考文献
Fleming, Ian; Floyd, Christopher D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 969 - 976
反应条件
1: 23 percent / tetrahydrofuran; various solvent(s) / 2 h / Ambient temperature 2: toluene-p-sulphonic acid / benzene / 12 h View Scheme
参考文献
Fleming, Ian; Floyd, Christopher D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 969 - 976
反应条件
1: tetrahydrofuran / 1.5 h / 0 °C 2: 1.) lithium / 1.) ether, overnight, 2.) 2 h, room temperature 3: 80 percent / methyl lithium / diethyl ether; tetrahydrofuran / 2 h / 0 °C 4: toluene-p-sulphonic acid / benzene / 12 h View Scheme
参考文献
Fleming, Ian; Floyd, Christopher D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 969 - 976
反应条件
1: 80 percent / methyl lithium / diethyl ether; tetrahydrofuran / 2 h / 0 °C 2: toluene-p-sulphonic acid / benzene / 12 h View Scheme
参考文献
Fleming, Ian; Floyd, Christopher D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 969 - 976
