1-苯基-2-丁烯-1-酮合成路线 （共 117 条）
反应条件
1: 1.) lithium / 1.) ether, overnight, 2.) 2 h, room temperature 2: 80 percent / methyl lithium / diethyl ether; tetrahydrofuran / 2 h / 0 °C 3: toluene-p-sulphonic acid / benzene / 12 h View Scheme
参考文献
Oare, David A.; Henderson, Mark A.; Sanner, Mark A.; Heathcock, Clayton H.
Journal of Organic Chemistry, 1990 , vol. 55, # 1 p. 132 - 157
反应条件
1: tris-(dibenzylideneacetone)dipalladium(0); tris(4-methylphenyl)-phosphine / toluene / 0.5 h / 100 °C / Inert atmosphere 2: tris-(dibenzylideneacetone)dipalladium(0); tris(4-methylphenyl)-phosphine / toluene / 12 h / 100 °C / Inert atmosphere View Scheme
参考文献
Rodriguez, Nuria; Manjolinho, Filipe; Gruenberg, Matthias F.; Goossen, Lukas J.
Chemistry - A European Journal, 2011 , vol. 17, # 49 p. 13688 - 13691
反应条件
methanesulfonyl chloride; triethylamine Yield given. Multistep reaction;
参考文献
Oare, David A.; Henderson, Mark A.; Sanner, Mark A.; Heathcock, Clayton H.
Journal of Organic Chemistry, 1990 , vol. 55, # 1 p. 132 - 157
反应条件
1.1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 0.25 h / 0 °C / Inert atmosphere 1.2: 6 h / Inert atmosphere 2.1: tris-(dibenzylideneacetone)dipalladium(0); tris(4-methylphenyl)-phosphine / 1,3,5-trimethyl-benzene / 12 h / 150 °C / Inert atmosphere View Scheme
参考文献
Rodriguez, Nuria; Manjolinho, Filipe; Gruenberg, Matthias F.; Goossen, Lukas J.
Chemistry - A European Journal, 2011 , vol. 17, # 49 p. 13688 - 13691
反应条件
DTPP-F6 Yield given. Multistep reaction;
参考文献
Kubota, Toshio; Miyashita, Satoshi; Kitazume, Tomoya; Ishikawa, Nobuo
Journal of Organic Chemistry, 1980 , vol. 45, # 25 p. 5052 - 5057
反应条件
cerium(III) iodide in tetrahydrofuran 1 h; Ambient temperature; Title compound not separated from byproducts;
参考文献
Fukuzawa, Shin-ichi; Fujinami, Tatsuo; Sakai, Shizuyoshi
Journal of the Chemical Society, Chemical Communications, 1985 , # 12 p. 777 - 778
反应条件
sodium hydride 1) hexamethylphosphoric triamide, 20 deg C 2) 80 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Snowden, Roger L.; Muller, Bernard L.; Schulte-Elte, Karl H.
Tetrahedron Letters, 1982 , vol. 23, # 3 p. 335 - 338
反应条件
copper(l) iodide 1.) ether, RT, 15 min; 2.) ether, RT, overnight; Yield given. Multistep reaction;
参考文献
Murahashi, Shun-Ichi; Mitsue, Yo; Tsumiyama, Tatsuo
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 9 p. 3285 - 3290
反应条件
T=10°C; 6 h; Irradiation;
参考文献
Izawa, Yasuji; Takeuchi, Masaki; Tomioka, Hideo
Chemistry Letters, 1983 , p. 1297 - 1300
反应条件
pyridine; pyridine-2-carboxylic acid; dihydrogen peroxide; iron(III) chloride; acetic acid T=20 - 22°C; 24 h; oxidations under var. conditions; Product distributionMechanism;
参考文献
Newcomb, Martin; Simakov, Pavel A.; Park, Seung-Un
Tetrahedron Letters, 1996 , vol. 37, # 6 p. 819 - 822
