3,3-二甲基茚满-5-醇合成路线 (共 5 条)
反应条件
phosphorous pentoxide; phosphoric acid in m-xylene
T=110°C; 1.5 h;
参考文献
PARADIGM THERAPEUTICS LTD.
Patent: WO2007/582 A1, 2007 ;
Location in patent: Page/Page column 35; 48 ;
WO 2007/000582 A1
反应条件
boron tribromide in dichloromethane
T=-78 - 20°C; 0.75 h;
参考文献
Phipps, Robert J.; Toste, F. Dean
Journal of the American Chemical Society, 2013 , vol. 135, # 4 p. 1268 - 1271
反应条件
in anhydrous xylene; water
参考文献
Bayer Aktiengesellschaft
Patent: US4107324 A1, 1978 ;
反应条件
sulfuryl dichloride; iodine in chloroform; water; acetic acid
参考文献
Bayer Aktiengesellschaft
Patent: US4107324 A1, 1978 ;
反应条件
bromine in tetrachloromethane
参考文献
Bayer Aktiengesellschaft
Patent: US4107324 A1, 1978 ;