双(2-羟基甲基苯基)硫化物合成路线 （共 14 条）
反应条件
in diethyl ether 72 h; Ambient temperature;
参考文献
Hellwinkel, Dieter; Bohnet, Siegbert
Chemische Berichte, 1987 , vol. 120, p. 1151 - 1174
反应条件
in diethyl ether 72 h; Ambient temperature;
参考文献
Hellwinkel, Dieter; Bohnet, Siegbert
Chemische Berichte, 1987 , vol. 120, p. 1151 - 1174
反应条件
sodium hydroxide in methanol; water 3 h; Inert atmosphereReflux;
参考文献
Du, Xian; Liu, Han; Du, Da-Ming
Tetrahedron Asymmetry, 2010 , vol. 21, # 2 p. 241 - 246
反应条件
thionyl chloride in methanol
2 h; Heating / reflux;
参考文献
XENON PHARMACEUTICALS INC.
Patent: US2008/234384 A1, 2008 ;
Location in patent: Page/Page column 46 ;
反应条件
pyridine; copper(I) oxide
T=115°C; 22 h; Inert atmosphere;
参考文献
Du, Xian; Liu, Han; Du, Da-Ming
Tetrahedron Asymmetry, 2010 , vol. 21, # 2 p. 241 - 246
参考文献
Hellwinkel, Dieter; Bohnet, Siegbert
Chemische Berichte, 1987 , vol. 120, p. 1151 - 1174
反应条件
1: 85 percent / SOCl2
2: 92 percent / thionyl chloride
View Scheme
参考文献
Hellwinkel, Dieter; Bohnet, Siegbert
Chemische Berichte, 1987 , vol. 120, p. 1151 - 1174
反应条件
1: 1.) NaOH, 2.) Cu powder / 1.) EtOH, H2O, 2.) 275 deg C
2: SOCl2 / 5 h / Heating
3: 1 h / Heating
View Scheme
参考文献
Raguse, Burkhard; Ridley, Damon D.
Australian Journal of Chemistry, 1988 , vol. 41, # 12 p. 1943 - 1952
反应条件
1: 1.) NaOH, 2.) Cu powder / 1.) EtOH, H2O, 2.) 275 deg C
2: SOCl2 / 5 h / Heating
3: 1 h / Heating
View Scheme
参考文献
Raguse, Burkhard; Ridley, Damon D.
Australian Journal of Chemistry, 1988 , vol. 41, # 12 p. 1943 - 1952
参考文献
Mayer
Chemische Berichte, 1910 , vol. 43, p. 590
