2-氯烟酰氯合成路线

参考文献

Springfield, Shawn A.; Marcantonio, Karen; Ceglia, Scott; Albaneze-Walker, Jennifer; Dormer, Peter G.; Nelson, Todd D.; Murry, Jerry A.
Journal of Organic Chemistry, 2003 , vol. 68, # 11 p. 4598 - 4599

49609-84-92-氯烟酰氯+

98-16-8间氨基三氟甲苯

53062-99-02-氯-N-(3-(三氟甲基)苯基)烟酰胺

参考文献

Amgen Inc.
Patent: US2003/225106 A1, 2003 ;
Location in patent: Page 116 ;

49609-84-92-氯烟酰氯+

75-31-0异丙胺

56904-63-3

参考文献

Zhang, Zhichao; Liu, Chengwu; Li, Xiangqian; Song, Ting; Wu, Zhiyong; Liang, Xiaomeng; Zhao, Yan; Shen, Xiaoyun; Chen, Hongbo
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 410 - 420

49609-84-92-氯烟酰氯+

540-37-4对碘苯胺

57841-58-4

参考文献

Cuffini, Silvia; Christopher, Glidewell; Low, John N.; De Oliveira, Aline G.; De Souza, Marcus V. N.; Vasconcelos, Thatyana R. A.; Wardell, Solange M. S. V.; Wardell, James L.
Acta Crystallographica Section B: Structural Science, 2006 , vol. 62, # 4 p. 651 - 665

49609-84-92-氯烟酰氯+

108-91-8环己胺

57841-70-0

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2008/12532 A2, 2008 ;
Location in patent: Page/Page column 54-55 ;
WO 2008/012532 A2

49609-84-92-氯烟酰氯+

109-89-7二乙胺

38029-99-12-氯-3-N,N-二乙基吡啶羧酰胺

参考文献

INCYTE CORPORATION
Patent: WO2007/38215 A1, 2007 ;
Location in patent: Page/Page column 88 ;
WO 2007/038215 A1

49609-84-92-氯烟酰氯

37891-04-62-三氧代-2,3-二氢吡啶并[2,3-d]嘧啶-4(1h)-酮

参考文献

Koscik; Kristian; Gonda; Dandarova
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 11 p. 3315 - 3328

49609-84-92-氯烟酰氯+

109-89-7二乙胺

54864-96-96-氯-N,N-二乙基-烟酰胺

参考文献

NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2007/71358 A1, 2007 ;
Location in patent: Page/Page column 23-24 ;
WO 2007/071358 A1

49609-84-92-氯烟酰氯+

106-40-1对溴苯胺

56149-25-8

参考文献

Cuffini, Silvia; Christopher, Glidewell; Low, John N.; De Oliveira, Aline G.; De Souza, Marcus V. N.; Vasconcelos, Thatyana R. A.; Wardell, Solange M. S. V.; Wardell, James L.
Acta Crystallographica Section B: Structural Science, 2006 , vol. 62, # 4 p. 651 - 665

49609-84-92-氯烟酰氯+

74497-02-2

56149-29-2

参考文献

Cativiela, C; Fernandez, J.; Melendez, E.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1093 - 1097