(2S)-2-{[(苄氧基)羰基]氨基}-8-[(2-甲基-2-丙基)氧基]-8-氧代辛酸-N-环己基环己胺(1:1)合成路线 （共 3 条）
反应条件
1: With lithium hydroxide; water in tetrahydrofuran
1.5 h;
2: With hydrogenchloride in tetrahydrofuran; water
pH=4 - 5;
参考文献
Attenni, Barbara; Ferrigno, Federica; Jones, Philip; Ingenito, Raffaele; Kinzel, Olaf; Llauger Bufi, Laura; Ontoria, Jesus Maria; Pescatore, Giovanna; Rowley, Michael; Scarpelli, Rita; Schultz, Carsten
Patent: US2009/48228 A1, 2009 ;
Location in patent: Page/Page column 90 ;
US 20090048228 A1
反应条件
1: Et3N
2: (i) H2SO4, (ii) aq. NaOH
View Scheme
参考文献
Kobayashi,A. et al.
Bulletin of the Chemical Society of Japan, 1969 , vol. 42, # 12 p. 3491 - 3495
反应条件
(i) H2SO4, (ii) aq. NaOH; Multistep reaction;
参考文献
Kobayashi,A. et al.
Bulletin of the Chemical Society of Japan, 1969 , vol. 42, # 12 p. 3491 - 3495
