5-(三氟甲基)吲哚-2-羧酸合成路线 (共 2 条)
反应条件
1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate in N,N-dimethyl-formamide T=105°C; 4 h; Inert atmosphere;
参考文献
Robertson, William M.; Kastrinsky, David B.; Hwang, Inkyu; Boger, Dale L.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 9 p. 2722 - 2725
反应条件
1: I2; Ag2SO4 / ethanol / 16 h / 20 °C 2: DABCO; Pd(OAc)2 / dimethylformamide / 4 h / 105 °C View Scheme
参考文献
Robertson, William M.; Kastrinsky, David B.; Hwang, Inkyu; Boger, Dale L.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 9 p. 2722 - 2725