反式-2-甲基-2-丁烯醛合成路线 （共 86 条）
反应条件
in toluene
T=100°C; Wittig Olefination; 24 h; Overall yield = 69 percent; Overall yield = 373 mg;
参考文献
Eske, Angelika; Goldfuss, Bernd; Griesbeck, Axel G.; De Kiff, Alan; Kleczka, Margarethe; Leven, Matthias; Neudoerfl, Joerg-M.; Vollmer, Moritz
Journal of Organic Chemistry, 2014 , vol. 79, # 4 p. 1818 - 1829
反应条件
1.1: Mg / tetrahydrofuran / 3 h / Heating
1.2: 83 percent / tetrahydrofuran / Heating
2.1: 75 percent / pyridinium chlorochromate; celite(R) / CH2Cl2 / 6 h / 20 °C
View Scheme
参考文献
Kraft, Philip; Popaj, Kasim; Abate, Agnese
Synthesis, 2005 , # 16 art. no. T09605SS, p. 2798 - 2809
反应条件
1: tetrahydrofuran / 2 h
2: Et3N, N,N-dimethylaminopyridine (DMAP) / CH2Cl2 / Ambient temperature; 2-3 h
View Scheme
参考文献
Fleming, Ian; Higgins, Dick; Lawrence, Nicholas J.; Thomas, Andrew P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 24 p. 3331 - 3350
反应条件
1: aqueous hydrochloric acid; arsenic acid; zinc chloride
2: katalytische Reduktion
3: H3aso4; ZnCl2; concentrated aqueous HCl
View Scheme
参考文献
Case; Brennan
Journal of Organic Chemistry, 1954 , vol. 19, p. 919,921
反应条件
hydrogenchloride; orthoarsenic acid; zinc(II) chloride
参考文献
Case; Brennan
Journal of Organic Chemistry, 1954 , vol. 19, p. 919,921
反应条件
in dichloromethane
0.5 h; Ambient temperature;
参考文献
Bestmann, Hans Juergen; Frey, Herbert
Liebigs Annalen der Chemie, 1980 , # 12 p. 2061 - 2071
