4’-甲基[1,1’-联苯]-4-甲酸甲酯合成路线 （共 47 条）
反应条件
Pd/BMI-TFSI; caesium carbonate in water T=80°C; Suzuki-Miyaura coupling; Inert atmosphere;
参考文献
Oda, Yoshiro; Hirano, Koji; Yoshii, Kazuki; Kuwabata, Susumu; Torimoto, Tsukasa; Miura, Masahiro
Chemistry Letters, 2010 , vol. 39, # 10 p. 1069 - 1071
反应条件
1: K3PO4; N-[(4-diphenylphosphinophenyl)methyl] D-gluconamide / PdCl2(GLCAphos)2 / H2O / 16 h / 80 °C 2: BF3*OEt2 / Heating View Scheme
参考文献
Santhosh; Paul; De Clercq; Pannecouque; Witvrouw; Loftus; Turpin; Buckheit, Jr.; Cushman
Journal of Medicinal Chemistry, 2001 , vol. 44, # 5 p. 703 - 714
反应条件
1,3-bis-(diphenylphosphino)propane; potassium carbonate; nickel dichloride in 1,4-dioxane T=100°C; Suzuki-Miyaura coupling; Inert atmosphere;
参考文献
Zhao, Yu-Long; Li, You; Li, Yu; Gao, Lian-Xun; Han, Fu-She
Chemistry - A European Journal, 2010 , vol. 16, # 17 p. 4991 - 4994
反应条件
SPHOS; tris-(dibenzylideneacetone)dipalladium(0); nonafluoro-n-butanesulfonyl fluoride; caesium carbonate in acetonitrile T=60°C; Suzuki-Miyaura Coupling; 9 h; Inert atmosphere;
参考文献
Ikawa, Takashi; Saito, Kozumo; Akai, Shuji
Synlett, 2012 , vol. 23, # 15 p. 2241 - 2246
反应条件
[Ni0(1,5-cyclooctadiene)2]; zirconium (IV) fluoride; cesium fluoride; tri-cyclo-hexyl-phosphine in toluene T=20 - 100°C; Suzuki-Miyaura coupling; 12 h; Inert atmosphere;
参考文献
Tobisu, Mamoru; Xu, Tian; Shimasaki, Toshiaki; Chatani, Naoto
Journal of the American Chemical Society, 2011 , vol. 133, # 48 p. 19505 - 19511
反应条件
bis-triphenylphosphine-palladium(II) chloride; lithium chloride in N,N-dimethyl-formamide Inert atmosphere;
参考文献
Sanchez, Ana I.; Martinez-Barrasa, Valentin; Burgos, Carolina; Vaquero, Juan J.; Alvarez-Builla, Julio; Terricabras, Emma; Segarra, Victor
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 8 p. 2370 - 2378
反应条件
1: K3PO4; N-[(4-diphenylphosphinophenyl)methyl] D-gluconamide / PdCl2(GLCAphos)2 / H2O / 16 h / 80 °C 2: BF3*OEt2 / Heating View Scheme
参考文献
Nishimura, Masato; Ueda, Masato; Miyaura, Norio
Tetrahedron, 2002 , vol. 58, # 29 p. 5779 - 5787
反应条件
1: 66 percent / K3PO4; 2-(dicyclohexylphosphino)biphenyl based D-gluconamide / Pd(OAc)2 / H2O / 16 h / 80 °C 2: BF3*OEt2 / Heating View Scheme
参考文献
Nishimura, Masato; Ueda, Masato; Miyaura, Norio
Tetrahedron, 2002 , vol. 58, # 29 p. 5779 - 5787
反应条件
1: PdCl2; aq. NaOH 2: benzene; methanol; hexane View Scheme
参考文献
Paul, Gitendra C.; De Clercq, Erik; Pannecouque, Christophe; Witvrouw, Myriam; Loftus, Tracy L.; Turpin, Jim A.; Buckheit Jr., Robert W.; Cushman, Mark
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 18 p. 2149 - 2152
反应条件
1: C15H13O2Pol With trifluoroacetic acid in dichloromethane T=20°C; 0.833333 h; Wang resin; 2: diazomethane
参考文献
Traficante, Carla I.; Delpiccolo, Carina M. L.; Mata, Ernesto G.
ACS Combinatorial Science, 2014 , vol. 16, # 5 p. 211 - 214
