1-乙基-5-羟基-2-甲基-1H-吲哚-3-羧酸乙酯合成路线 （共 3 条）
反应条件
1: aqueous NaOH; dioxane 2: aqueous NaOH View Scheme
参考文献
Grinew et al.
Zhurnal Obshchei Khimii, 1957 , vol. 27, p. 1690,1692; engl. Ausg. S. 1759, 1761
反应条件
1: ethyl acetoacetate; ethylamine in methanol
T=20°C;
2: p-benozquinone With acetic acid
T=20°C; Nenitzescu reaction; Further stages.;
参考文献
Boehme, Thomas M.; Augelli-Szafran, Corinne E.; Hallak, Hussein; Pugsley, Thomas; Serpa, Kevin; Schwarz, Roy D.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 14 p. 3094 - 3102
参考文献
Grinew et al.
Zhurnal Obshchei Khimii, 1957 , vol. 27, p. 1690,1692; engl. Ausg. S. 1759, 1761
