N,N'-二环己基-4-吗啉脒合成路线 (共 4 条)
反应条件
Sm[N(TMS)2]2(THF)3 T=80°C; 3 h; Inert atmosphere;
参考文献
Du, Zhu; Li, Wenbo; Zhu, Xuehua; Xu, Fan; Shen, Qi
Journal of Organic Chemistry, 2008 , vol. 73, # 22 p. 8966 - 8972
反应条件
in tetrahydrofuran; chloroform a) RT, 2 h, b) reflux, 2 h;
参考文献
Perricone; Humphrey; Skaletzky; Graham; Zandt; Zins
Journal of Medicinal Chemistry, 1994 , vol. 37, # 22 p. 3693 - 3700
反应条件
1: COCl2 / tetrahydrofuran / 18 h / Ambient temperature 2: 60.5 percent / CHCl3; tetrahydrofuran / a) RT, 2 h, b) reflux, 2 h View Scheme
参考文献
Perricone; Humphrey; Skaletzky; Graham; Zandt; Zins
Journal of Medicinal Chemistry, 1994 , vol. 37, # 22 p. 3693 - 3700
反应条件
in dichloromethane 22 h; Ambient temperature;
参考文献
Thomas; Nishizawa; Zimmermann; Williams
Journal of Medicinal Chemistry, 1989 , vol. 32, # 1 p. 228 - 236