4-溴-1-甲基-5-(三氟甲基)-1H-吡唑合成路线 （共 4 条）
反应条件
bromine; iron T=100°C; 1 h;
参考文献
Schlosser, Manfred; Volle, Jean-Noel; Leroux, Frederic; Schenk, Kurt
European Journal of Organic Chemistry, 2002 , # 17 p. 2913 - 2920
反应条件
1: 70 percent / diisopropylamine; butyllithium / tetrahydrofuran; hexane / 0.08 h / -75 °C 2: 93 percent / zinc; NaOH / H2O / 1 h / 25 °C View Scheme
参考文献
Schlosser, Manfred; Volle, Jean-Noel; Leroux, Frederic; Schenk, Kurt
European Journal of Organic Chemistry, 2002 , # 17 p. 2913 - 2920
反应条件
1: 4-bromo-1-methyl-5-(trifluoromethyl)pyrazole With tert.-butyl lithium in diethyl ether; pentane T=-75°C; 0.0833333 h; 2: N,N-dimethyl-formamide Further stages.;
参考文献
Schlosser, Manfred; Volle, Jean-Noel; Leroux, Frederic; Schenk, Kurt
European Journal of Organic Chemistry, 2002 , # 17 p. 2913 - 2920
反应条件
1: 4-bromo-1-methyl-5-(trifluoromethyl)pyrazole With tert.-butyl lithium in diethyl ether; pentane T=-75°C; 0.0833333 h; 2: carbon dioxide Further stages.;
参考文献
European Journal of Organic Chemistry, , # 17 p. 2913 - 2920
