1-(4-二甲基氨基-1-哌啶基)乙酮合成路线 （共 3 条）
反应条件
sodium cyanoborohydride in hydrogenchloride; ethanol
T=20°C; pH=6; 96 h;
参考文献
Kobashi, Seiichi; Kubo, Hajime; Yamauchi, Takayasu; Higashiyama, Kimio
Biological and Pharmaceutical Bulletin, 2002 , vol. 25, # 8 p. 1030 - 1034
反应条件
1: 99 percent / dimethylaminopyridine; triethylamine / CH2Cl2 / 1 h / 0 °C / under nitrogen
2: 70 percent / HCl / methanol / 19 h / 20 °C
3: 53 percent / NaBH3Cn / ethanol; HCl / 96 h / 20 °C / pH 6
View Scheme
参考文献
Kobashi, Seiichi; Kubo, Hajime; Yamauchi, Takayasu; Higashiyama, Kimio
Biological and Pharmaceutical Bulletin, 2002 , vol. 25, # 8 p. 1030 - 1034
反应条件
1: 70 percent / HCl / methanol / 19 h / 20 °C
2: 53 percent / NaBH3Cn / ethanol; HCl / 96 h / 20 °C / pH 6
View Scheme
参考文献
Kobashi, Seiichi; Kubo, Hajime; Yamauchi, Takayasu; Higashiyama, Kimio
Biological and Pharmaceutical Bulletin, 2002 , vol. 25, # 8 p. 1030 - 1034
