6-[4-[(4-乙基-1-哌嗪)甲基]苯基]-N-[(1R)-1-苯基乙基]-7H-吡咯并[2,3-d]嘧啶-4-胺合成路线 （共 2 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=25 - 50°C; 3 h; 2: With water in tetrahydrofuran 2.5 h; Product distribution / selectivity;
参考文献
WO2007/17468 A2, ;
Page/Page column 7-8 ;
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=25 - 50°C; 3 h; 2: With water in tetrahydrofuran 2.5 h; 3: With sodium hydroxide; sodium tetrahydroborate; water; acetic acid Product distribution / selectivity; more than 3 stages;
参考文献
WO2007/17468 A2, ;
Page/Page column 7-8 ;
