4-羟基-3-甲氧基苄醇合成路线 （共 134 条）
反应条件
1: K2CO3 / ethanol 2: HCl / CH2Cl2 View Scheme
参考文献
Andresen; Davis; Long
Journal of Pharmaceutical Sciences, 1979 , vol. 68, # 3 p. 283 - 288
反应条件
1: 60 percent / dimethylformamide / 20 h / 130 °C 2: 82 percent / H2; HCl / Pd/C / ethanol / 12 h / 20 °C View Scheme
参考文献
Jai, Woong Seo; Srisook, Ekaruth; Hyo, Jin Son; Hwang, Onyou; Cha, Young-Nam; Dae, Yoon Chi
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 14 p. 3369 - 3373
反应条件
di-isopropyl azodicarboxylate; thiamine diphosphate in tetrahydrofuran T=20°C; Mitsunobu esterification; 24 h;
参考文献
Appendino, Giovanni; Minassi, Alberto; Daddario, Nives; Bianchi, Federica; Tron, Gian Cesare
Organic Letters, 2002 , vol. 4, # 22 p. 3839 - 3841
反应条件
Novozym 435; 4 Angstroem MS in 1,4-dioxane T=25°C; 20 h;
参考文献
Kobata, Kenji; Kawaguchi, Manami; Watanabe, Tatsuo
Bioscience, Biotechnology and Biochemistry, 2002 , vol. 66, # 2 p. 319 - 327
反应条件
cerium(III) chloride in tetrahydrofuran T=20°C; 12 h; Product distribution; Further Variations:Reaction partnersReagents;
参考文献
Torregiani, Elisabetta; Seu, Gianfranco; Minassi, Alberto; Appendino, Giovanni
Tetrahedron Letters, 2005 , vol. 46, # 13 p. 2193 - 2196
反应条件
1: 40.5 percent / Et3N / ethyl acetate / 1.) 12 h, 2.) reflux, 2 h 2: 49 percent / pyrrolidine View Scheme
参考文献
Walpole; Wrigglesworth; Bevan; Campbell; Dray; James; Masdin; Perkins; Winter
Journal of Medicinal Chemistry, 1993 , vol. 36, # 16 p. 2373 - 2380
反应条件
pyridine T=20°C; 24 h; Product distribution; Further Variations:Reaction partnersReagents;
参考文献
Appendino, Giovanni; Minassi, Alberto; Daddario, Nives; Bianchi, Federica; Tron, Gian Cesare
Organic Letters, 2002 , vol. 4, # 22 p. 3839 - 3841
反应条件
sodium tetrahydroborate; 1 Pd/C; water; potassium hydroxide in methanol T=20°C; 72 h; In air;
参考文献
An, Gwangil; Ahn, Hyunseok; De Castro, Kathlia A.; Rhee, Hakjune
Synthesis, 2010 , # 3 art. no. F19009SS, p. 477 - 485
反应条件
tricobalt tetroxide; oxygen in isopropyl alcohol T=80°C; P=5100.51 Torr; 6 h; Autoclave;
参考文献
Jha, Ajay; Rode, Chandrashekhar V.
New Journal of Chemistry, 2013 , vol. 37, # 9 p. 2669 - 2674
反应条件
dihydrogen peroxide; acetic acid; methyltrioxorhenium(VII) supported on poly(4-vinylpyridine) T=20°C; 6 h; Product distribution; Further Variations:Catalysts;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 15 p. 5292 - 5302
