4'-羟基-3'-甲氧基苯乙酮合成路线 （共 147 条）
反应条件
1: triethylamine / dichloromethane 2: CM-phos; palladium diacetate; potassium carbonate / water / 18 h / 80 °C / Inert atmosphere View Scheme
参考文献
Yeung, Pui Yee; So, Chau Ming; Lau, Chak Po; Kwong, Fuk Yee
Angewandte Chemie - International Edition, 2010 , vol. 49, # 47 p. 8918 - 8922
反应条件
sodium hydroxide; iodine T=65°C; 4 h;
参考文献
Balram; Ram; Ram, S. Raghu
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2003 , vol. 42, # 9 p. 2059 - 2062
反应条件
1: aqueous KI; NaHCO3; iodine 2: copper; methanol / 140 °C View Scheme
参考文献
Crawford et al.
Canadian Journal of Chemistry, 1956 , vol. 34, p. 1562,1564,1565
参考文献
Bjorsvik, Hans-Rene; Norman, Kristine
Organic Process Research and Development, 1999 , vol. 3, # 5 p. 341 - 346
反应条件
sodium hydroxide in N,N-dimethyl acetamide T=25°C; Rate constant;
参考文献
Cork, David G.; Hayashi, Nobuyoshi
Bulletin of the Chemical Society of Japan, 1993 , vol. 66, # 5 p. 1583 - 1585
反应条件
potassium carbonate in acetonitrile T=20 - 85°C; 8 h;
参考文献
Kilaru, Ravendra Babu; Kuruva, Chandra Sekhar; Katla, Venkata Ramana; Chamarthi, Naga Raju
Asian Journal of Chemistry, 2013 , vol. 25, # 10 p. 5307 - 5310
反应条件
tetrabutylammomium bromide; potassium carbonate in acetonitrile T=80°C; Industry scale;
参考文献
LUPIN LIMITED; ANSARI, Shahid, Akhtar; HIRPARA, Hitin, Maganbhai; YADAV, Ashok, Keshavlal; GIANCHANDANI, Jaya, Parasram
Patent: WO2012/164516 A1, 2012 ;
Location in patent: Page/Page column 4-5 ;
反应条件
potassium carbonate in acetone
参考文献
Slyn'Ko; Tatarova; Shakirov; Shul'Ts
Chemistry of Natural Compounds, 2013 , vol. 49, # 2 p. 294 - 301
Khim. Prir. Soedin., 2013 , # 2 p. 250 - 256,7
反应条件
1: 0.42 g / 90percent orthophosphoric acid / petroleum ether / 12 h / 30 - 35 °C 2: 0.075 g / DDQ / benzene / 12 h / Heating View Scheme
参考文献
Ahluwalia, V. K.; Arora, K. K.; Manchanda, Saroj
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 11 p. 1039 - 1040
反应条件
potassium carbonate in butanone T=78 - 80°C;
参考文献
Vertessy, Miklos
Patent: US2010/76196 A1, 2010 ;
Location in patent: Page/Page column 3 ;
