4'-羟基-3'-甲氧基苯乙酮合成路线 （共 147 条）
反应条件
pyridine in dichloromethane Ambient temperature;
参考文献
Ponzo, Viviana L.; Kaufman, Teodoro S.
Tetrahedron Letters, 1995 , vol. 36, # 50 p. 9105 - 9108
反应条件
pyridine; sodium hydroxide 1) acetone, r.t., 2) 90 deg C, 50 min.; Yield given. Multistep reaction;
参考文献
Delay; Cizeau; Delmotte
Carbohydrate Research, 1992 , vol. 225, # 2 p. 179 - 188
反应条件
Yield given. Multistep reaction;
参考文献
Delay, Didier; Delmotte, Francis
Carbohydrate Research, 1990 , vol. 198, # 2 p. 223 - 234
反应条件
1: 82 percent / K2CO3, Bu4NI / H2O; tetrahydrofuran / 10 h / 80 °C 2: 63 percent / POCl3 / 1) 0 deg C, 20 min, 2) 65 deg C, 10 h 3: 79 percent / NaOH / H2O; dioxane / 2 h / 80 °C View Scheme
参考文献
Yang, Zhen; Liu, Han Biao; Lee, Chi Ming; Chang, Hson Mou; Wong, Henry N. C.
Journal of Organic Chemistry, 1992 , vol. 57, # 28 p. 7248 - 7257
反应条件
sodium hydride 1.) THF, DMF, RT, 3 h, 2.) THF, DMF, RT, 2 h; Yield given. Multistep reaction;
参考文献
Maeda; Masuda; Tokoroyama
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 9 p. 1588 - 1591
反应条件
NaH in water; N,N-dimethyl-formamide
参考文献
Huang, Yih; Huang, Tai-Nang; Shen, Ming
Patent: US2001/44530 A1, 2001 ;
反应条件
1: 47 percent / cupric bromide / CHCl3; ethyl acetate / 4 h / 20 °C 2: DBU / dioxane / 12 h / 0 - 20 °C 3: TFA / 4 h / 0 °C 4: H2O / UV-irradiation View Scheme
参考文献
Conrad II, Peter G.; Givens, Richard S.; Weber, Joerg F. W.; Kandler, Karl
Organic Letters, 2000 , vol. 2, # 11 p. 1545 - 1547
反应条件
1.1: copper(I) bromide / ethanol 2.1: sodium / ethanol 2.2: Cooling with ice View Scheme
参考文献
Song, Qi; Wang, Feng; Xu, Jie
Chemical Communications, 2012 , vol. 48, # 56 p. 7019 - 7021
反应条件
nitric acid; acetic acid T=20°C; 0.5 h;
参考文献
Egorov, Maxim; Delpech, Bernard; Aubert, Genevieve; Cresteil, Thierry; Garcia-Alvarez, Maria Concepcion; Collin, Pascal; Marazano, Christian
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 9 p. 1518 - 1524
反应条件
1,4-dioxane; copper (II) chromite T=275°C; P=147102 Torr; Hydrogenation;
参考文献
Brewer; Cooke; Hibbert
Journal of the American Chemical Society, 1948 , vol. 70, p. 57
