4'-羟基-3'-甲氧基苯乙酮合成路线 （共 147 条）
反应条件
1.1: potassium carbonate / potassium iodide / acetone / 48 h / Reflux 2.1: nitric acid; acetic acid / 18 h / 10 - 20 °C 3.1: zinc; ammonium chloride / ethanol; water / 5 h / Reflux 4.1: sodium methylate / ethylene glycol dimethyl ether / 1 h / 0 °C 4.2: 0 - 20 °C View Scheme
参考文献
MAX-PLANCK-GESELLSCHAFT ZUR FOeRDERUNG DER WISSENSCHAFTEN E.V.; ULLRICH, Axel; TORKA, Robert; ZHANG, Yixiang; KERI, Gyoergy; OeRFI, Laszlo; SZABADKAI, Istvan
Patent: WO2011/45084 A1, 2011 ;
WO 2011/045084 A1
反应条件
sodium hydroxide; nitrobenzene T=160°C;
参考文献
v.Wacek; Kratzl
Chemische Berichte, 1943 , vol. 76, p. 891,893
参考文献
v.Wacek; Kratzl
Chemische Berichte, 1943 , vol. 76, p. 891,893
反应条件
sodium hydroxide; nickel monoaluminide T=90°C;
参考文献
Journal of Organic Chemistry, , vol. 9, p. 1,5
参考文献
Journal of Organic Chemistry, , vol. 9, p. 1,5
反应条件
sodium hydroxide in ethanol; water
参考文献
Weber, Waylon M.; Hunsaker, Lucy A.; Abcouwer, Steve F.; Deck, Lorraine M.; Vander Jagt, David L.
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 11 p. 3811 - 3820
反应条件
1: 47 percent / cupric bromide / CHCl3; ethyl acetate / 4 h / 20 °C 2: DBU / dioxane / 12 h / 0 - 20 °C 3: TFA / 4 h / 0 °C 4: H2O / UV-irradiation View Scheme
参考文献
Conrad II, Peter G.; Givens, Richard S.; Weber, Joerg F. W.; Kandler, Karl
Organic Letters, 2000 , vol. 2, # 11 p. 1545 - 1547
反应条件
1: sodium hydroxide 2: sodium hydroxide; sodium hypochlorite / water / 2 h View Scheme
参考文献
Organic Process Research and Development, , vol. 3, # 5 p. 341 - 346
反应条件
sodium tetrahydroborate in ethanol 3 h; Ambient temperature;
参考文献
Journal of the Chemical Society. Perkin Transactions 2, , vol. 6, p. 1131 - 1138
反应条件
hydrogenchloride; sodium cyanoborohydride in methanol 18 h; Product distribution;
参考文献
Synthetic Communications, , vol. 15, # 14 p. 1315 - 1324
