2-氮杂双环[2.2.1]庚-5-烯-3-酮合成路线 （共 59 条）
参考文献
Kuraray Co., Ltd.
Patent: US6060609 A1, 2000 ;
反应条件
acetic acid in dichloromethane; water
参考文献
Lonza Ltd.
Patent: US5200527 A1, 1993 ;
反应条件
1: in diethyl ether T=-60°C; 2 h; 2: With potassium hydroxide; sodium sulfite in diethyl ether T=0°C; 0.5 h;
参考文献
Besada; Gonzalez-Moa; Teran; Santana; Uriarte
Synthesis, 2002 , # 16 p. 2445 - 2449
反应条件
acetic acid in dichloromethane 1) 10 deg C, 3 h, 2) 20 deg C, 1 h;
参考文献
Heesing, Albert; Herdering, Wilhelm
Chemische Berichte, 1983 , vol. 116, # 3 p. 1081 - 1096
反应条件
1: CH2Cl2 / 2 h / Ambient temperature 2: AcOH / CH2Cl2 / 1 h / Ambient temperature View Scheme
参考文献
Griffiths, Gareth J.; Previdoli, Felix E.
Journal of Organic Chemistry, 1993 , vol. 58, # 22 p. 6129 - 6131
反应条件
sodium thiosulfate Yield given;
参考文献
Pham, Phuong-T.; Vince, Robert
Phosphorus, Sulfur and Silicon and the Related Elements, 2007 , vol. 182, # 4 p. 779 - 791
参考文献
Morgan, Paul E.; McCague, Ray; Whiting, Andrew
Chemical Communications, 1996 , # 15 p. 1811 - 1812
反应条件
l-menthol ethylaluminum dichloride; water 1.) CH2Cl2, -25 deg C, 24 h, 2. ) CH2Cl2; Yield given. Multistep reaction;
参考文献
Katagiri, Nobuya; Makino, Masashi; Tamura, Takahiro; Kaneko, Chikara
Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 4 p. 850 - 852
反应条件
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 °C / Reflux 1.2: 0 °C 1.3: 12 h / 20 °C 2.1: ozone / dichloromethane; methanol / -78 °C / Inert atmosphere 2.2: 16 h / -78 °C 2.3: 1 h / -78 - 20 °C View Scheme
参考文献
Targacept, Inc.
Patent: US2011/263629 A1, 2011 ;
US 20110263629 A1
反应条件
lipase B from Candida antarctica in water; isopropyl alcohol T=60°C; 4 h; Enzymatic reaction; stereospecific reaction;
参考文献
Kiss, Lorand; Forro, Enikoe; Sillanpaeae, Reijo; Fueloep, Ferenc
Synthesis, 2010 , # 1 art. no. T13309SS, p. 153 - 160
