2-氮杂双环[2.2.1]庚-5-烯-3-酮合成路线 （共 59 条）
反应条件
cloned (+)-γ-lactamase T=25°C; Ring cleavage; pH=7.5; 1 h;
参考文献
Smith, Mark E.B.; Lloyd, Michael C.; Derrien, Nadine; Lloyd, Richard C.; Taylor, Stephen J.C.; Chaplin, David A.; Casy, Guy; McCague, Raymond
Tetrahedron Asymmetry, 2001 , vol. 12, # 5 p. 703 - 705
反应条件
3,3-dimethyldioxirane in dichloromethane; acetone T=20°C; 36 h;
参考文献
Legraverend, Michel; Bisagni, Emile; Huel, Christiane
Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 1881
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane Epoxidation;
参考文献
Dominguez, Belen M.; Cullis, Paul M.
Tetrahedron Letters, 1999 , vol. 40, # 31 p. 5783 - 5786
反应条件
hydrogen; palladium 10 on activated carbon in ethyl acetate T=20°C; 24 h;
参考文献
MERCK and CO., INC
Patent: WO2005/120505 A2, 2005 ;
Location in patent: Page/Page column 29-30 ;
WO 2005/120505 A2
反应条件
cloned (+)-γ-lactamase T=25°C; Ring cleavage; pH=7.5; 1 h;
参考文献
Smith, Mark E.B.; Lloyd, Michael C.; Derrien, Nadine; Lloyd, Richard C.; Taylor, Stephen J.C.; Chaplin, David A.; Casy, Guy; McCague, Raymond
Tetrahedron Asymmetry, 2001 , vol. 12, # 5 p. 703 - 705
反应条件
hydrogenchloride Hydrolysis; 12 h;
参考文献
Taylor, Stephen J C; McCague, Raymond; Wisdom, Richard; Lee, Carol; Dickson, Karen; et al.
Tetrahedron: Asymmetry, 1993 , vol. 4, # 6 p. 1117 - 1128
反应条件
lipase B from Candida antarctica in water; isopropyl alcohol T=60°C; 4 h; Enzymatic reaction; stereospecific reaction;
参考文献
Kiss, Lorand; Forro, Enikoe; Sillanpaeae, Reijo; Fueloep, Ferenc
Synthesis, 2010 , # 1 art. no. T13309SS, p. 153 - 160
反应条件
T=22°C; 16 h; ENZA-25 cells;
参考文献
Nakano, Hiroto; Iwasa, Kazuto; Okuyama, Yuko; Hongo, Hiroshi
Tetrahedron Asymmetry, 1996 , vol. 7, # 8 p. 2381 - 2386
反应条件
lipase B from Candida antarctica in water; isopropyl alcohol T=60°C; 4 h; Enzymatic reaction; stereospecific reaction;
参考文献
Kiss, Lorand; Forro, Enikoe; Sillanpaeae, Reijo; Fueloep, Ferenc
Synthesis, 2010 , # 1 art. no. T13309SS, p. 153 - 160
反应条件
T=22°C; 16 h; ENZA-25 cells;
参考文献
Nakano, Hiroto; Iwasa, Kazuto; Okuyama, Yuko; Hongo, Hiroshi
Tetrahedron Asymmetry, 1996 , vol. 7, # 8 p. 2381 - 2386
