1-羟基-3-苯基-丙-2-酮合成路线 （共 25 条）
反应条件
palladium diacetate; tributylphosphine
T=100°C;
参考文献
Horikawa, Manabu; Nakajima, Terumi; Ohfune, Yasufumi
Synlett, 1997 , vol. 1997, # 3 p. 253 - 254
反应条件
1: in diethyl ether
T=20°C; 1 h;
2: With boron trifluoride diethyl etherate in tert-butyl alcohol
T=70°C; 1 h;
参考文献
Guo, Zhiwei; Goswami, Animesh; Nanduri, Venkata B.; Patel, Ramesh N.
Tetrahedron Asymmetry, 2001 , vol. 12, # 4 p. 571 - 577
反应条件
hydrogenchloride in acetic acid
T=120°C; 0.666667 h;
参考文献
Shin-Watanabe,T.; Fukuhara,K.; Murao,S.
Tetrahedron, 1982 , vol. 38, p. 1775
反应条件
1: 86 percent / NaOH / acetonitrile / 3 h / 75 °C
2: 83 percent / 1N H2SO4 / ethanol / 16 h / 50 °C
View Scheme
参考文献
See Waters, Marjorie; Cowen, Jennifer A.; McWilliams, J. Christopher; Maligres, Peter E.; Askin, David
Tetrahedron Letters, 2000 , vol. 41, # 2 p. 141 - 144
反应条件
1: 50 percent / lithium bis(trimethylsilyl)amide / tetrahydrofuran; hexamethylphosphoric acid triamide / 1 h / Ambient temperature
2: 82 percent / LiAlH4 / tetrahydrofuran / -100 - 20 °C
View Scheme
参考文献
Dalla; Catteau
Tetrahedron, 1999 , vol. 55, # 21 p. 6497 - 6510
反应条件
1: 64 percent
2: H2SO4 / dioxane
View Scheme
参考文献
Asano; Yamada; Kato; Yamaguchi; Hibino; Hirai; Kondo
Journal of Organic Chemistry, 1990 , vol. 55, # 21 p. 5567 - 5571
反应条件
[AuClPh3P]; silver trifluoromethanesulfonate in anhydrous dichloroethane
T=20°C;
参考文献
Dai, Lun-Zhi; Shi, Min
Chemistry - A European Journal, 2008 , vol. 14, # 23 p. 7011 - 7018
反应条件
triethylamine; 3-ethylbenzothiazolium bromide
Heating;
参考文献
Rosowsky; Fu; Queener
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 5 p. 1197 - 1202
反应条件
1: 88 percent / pyridine / 4 h / Ambient temperature
2: 1.) O3, 2.) Ph3P polymer / 1.) CH2Cl2, -78 deg C, 7 min, 2.) CH2Cl2, 2 h
3: 88 percent / LiBF4 / acetonitrile; CH2Cl2 / 15 h / Ambient temperature
View Scheme
参考文献
Ferraboschi, Patrizia; Grisenti, Paride; Manzocchi, Ada; Santaniello, Enzo
Tetrahedron, 1994 , vol. 50, # 35 p. 10539 - 10548
反应条件
1: 1.) O3, 2.) Ph3P polymer / 1.) CH2Cl2, -78 deg C, 7 min, 2.) CH2Cl2, 2 h
2: 88 percent / LiBF4 / acetonitrile; CH2Cl2 / 15 h / Ambient temperature
View Scheme
参考文献
Ferraboschi, Patrizia; Grisenti, Paride; Manzocchi, Ada; Santaniello, Enzo
Tetrahedron, 1994 , vol. 50, # 35 p. 10539 - 10548
