(R)-(-)-1-甲氧基-2-丙醇合成路线 (共 11 条)
反应条件
potassium isopropoxide; isopropyl alcohol; [Ru(II)(η6-benzene)(μ-Cl)Cl]2; (1S,2R)-N-benzylnorephedrine T=20°C; 0.33 h; Title compound not separated from byproducts;
参考文献
Everaere, Kathelyne; Carpentier, Jean-Francois; Mortreux, Andre; Bulliard, Michel
Tetrahedron Asymmetry, 1999 , vol. 10, # 21 p. 4083 - 4086
反应条件
Cu(L-Asp)(1,2-bis(4-pyridyl)ethylene)0.5(H2O)0.5(MeOH)0.5 T=25°C;
参考文献
Ingleson, Michael J.; Barrio, Jorge Perez; Bacsa, John; Dickinson, Calum; Park, Hyunsoo; Rosseinsky, Matthew J.
Chemical Communications, 2008 , # 11 p. 1287 - 1289
反应条件
vinyl acetate; Candida antarctica B lipase on carrier B in phosphate buffer T=37°C; pH=7.3; 3.41667 h;
参考文献
Baumann, Markus; Hauer, Bernhard H.; Bornscheuer, Uwe T.
Tetrahedron Asymmetry, 2000 , vol. 11, # 23 p. 4781 - 4790
反应条件
vinyl acetate; Candida antarctica B lipase on carrier C3 in hexane T=37°C; 20 h; Title compound not separated from byproducts;
参考文献
Baumann, Markus; Hauer, Bernhard H.; Bornscheuer, Uwe T.
Tetrahedron Asymmetry, 2000 , vol. 11, # 23 p. 4781 - 4790
反应条件
sodium phosphate buffer; esterase B from Candida antarctica in water T=37°C; pH=7.3; 1 h; Product distribution; Further Variations:Reagents;
参考文献
Baumann, Markus; Stuermer, Rainer; Bornscheuer, Uwe T.
Angewandte Chemie - International Edition, 2001 , vol. 40, # 22 p. 4201 - 4204
参考文献
Inoue et al.
Makromolekulare Chemie, 1966 , vol. 90, p. 131,133
反应条件
monofluoromethane T=25°C; P=720 Torr; Irradiationalso in the presence of H2O or CH4; Product distributionMechanism;
参考文献
Troiani, Anna; Filippi, Antonello; Speranza, Maurizio
Chemistry - A European Journal, 1997 , vol. 3, # 12 p. 2063 - 2070
反应条件
monofluoromethane T=25°C; P=720 Torr; Irradiationalso in the presence of H2O or CH4; Product distributionMechanism;
参考文献
Troiani, Anna; Filippi, Antonello; Speranza, Maurizio
Chemistry - A European Journal, 1997 , vol. 3, # 12 p. 2063 - 2070
反应条件
Lactobacillus brevis dehydrogenase; NADPH; tris(hydroxymethyl)methylamine hydrochloride in water; dimethyl sulfoxide T=30°C; Enzymatic reaction; Kinetics;
参考文献
Bisogno, Fabricio R.; Garcia-Urdiales, Eduardo; Valdes, Haydee; Lavandera, Ivan; Kroutil, Wolfgang; Suarez, Dimas; Gotor, Vicente
Chemistry - A European Journal, 2010 , vol. 16, # 36 p. 11012 - 11019
反应条件
triphenylphosphine on polystyrene in tetrahydrofuran T=0°C; 0.5 h; polymer-supported triphenyl phosphine;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2005/80359 A1, 2005 ;
Location in patent: Page/Page column 73 ;
WO 2005/080359 A1