2,4-二氯-5 硝基嘧啶合成路线 （共 28 条）
反应条件
N,N-dimethyl-aniline; trichlorophosphate Reflux;
参考文献
Hansen, Finn K.; Geffken, Detlef
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 2 p. 321 - 328
反应条件
diethylamine 70 h; Heating / reflux;
参考文献
DuPont Pharmaceuticals Company
Patent: US6342503 B1, 2002 ;
Location in patent: Example 105 ;
US 6342503 B1
反应条件
T=160 - 185°C; im Rohr;
参考文献
Isay
Chemische Berichte, 1906 , vol. 39, p. 252
反应条件
potassium hydrosulphide
参考文献
Inoue
Chemical and Pharmaceutical Bulletin, 1958 , vol. 6, p. 352,354
反应条件
1,1-diphenylthiourea in acetonitrile 0.333333 h; Ambient temperaturealso with other S=CR1R2, other reaction time; Product distribution;
参考文献
Kondo, Koichi; Komamura, Chiaki; Murakami, Mikio; Takemoto, Kiichi
Synthetic Communications, 1985 , vol. 15, # 3 p. 171 - 178
参考文献
Brown
Journal of Applied Chemistry, 1954 , vol. 4, p. 72,74
反应条件
1: With iron; acetic acid 14 h; 2: With sodium carbonate in water; ethyl acetate
参考文献
Burger, Matthew; Lindvall, Mika
Patent: US2011/195980 A1, 2011 ;
Location in patent: Page/Page column 17 ;
反应条件
triethylamine in ethanol; ethyl acetate
参考文献
Levy, Daniel; Marlowe, Charles; Kane-Maguire, Kim; Scarborough, Robert M.
Patent: US2002/68745 A1, 2002 ;
反应条件
T=-10 - 0°C; 0.166667 h;
参考文献
WO2007/118859 A1, ;
Page/Page column 119-120 ;
WO 2007/118859 A1
反应条件
benzoic acid in acetonitrile 0.166667 h; Ambient temperatureother reagents, reaction time, temperature, solvent; Product distribution;
参考文献
Kondo, Koichi; Komamura, Chiaki; Murakami, Mikio; Takemoto, Kiichi
Synthetic Communications, 1985 , vol. 15, # 3 p. 171 - 178
