反应条件
1: With 4-methyl-morpholine; hydroxylamine Wang resin; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
0.5 h;
2: With piperidine in N,N-dimethyl-formamide
0.166667 h;
3: With trifluoroacetic acid in dichloromethane
T=20°C; 0.5 h; Further stages.;
参考文献
Gu, Xianfeng; Wang, Yuehao; Kumar, Anil; Ye, Guofeng; Parang, Keykavous; Sun, Gongqin
Journal of Medicinal Chemistry, 2006 , vol. 49, # 25 p. 7532 - 7539