3-(3-甲氧基苯氧基)丙酸合成路线 （共 19 条）
反应条件
1: With sodium hydrogencarbonate in water 0.0833333 h; 2: 3-methoxy-phenol With sodium hydroxide in water T=100°C; 3 h; 3: With hydrogenchloride in water T=20°C;
参考文献
Wyeth
Patent: US2006/52410 A1, 2006 ;
Location in patent: Page/Page column 7; 10 ;
US 20060052410 A1
反应条件
1: With potassium hydroxide; sodium hydrogencarbonate in water T=110°C; 16 h; 2: With hydrogenchloride in water pH=5;
参考文献
MEMORY PHARMACEUTICALS CORPORATION
Patent: WO2009/55437 A2, 2009 ;
Location in patent: Page/Page column 59; 60 ;
反应条件
hydrogenchloride Heating1.5 - 3.5 h;
参考文献
Lai, Steven M. F.; Orchison, Jack J. A.; Whiting, Donald A.
Tetrahedron, 1989 , vol. 45, # 18 p. 5895 - 5906
反应条件
sodium hydroxide; sodium hydrogencarbonate in water T=100°C; 3 h;
参考文献
Vu, An T.; Campbell, Alison N.; Harris, Heather A.; Unwalla, Rayomand J.; Manas, Eric S.; Mewshaw, Richard E.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 14 p. 4053 - 4056
反应条件
sodium hydroxide; water T=100°C;
参考文献
Gresham et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 661
反应条件
sodium hydroxide in water
参考文献
Cao, Zhisong; Liehr, Joachim G.
Synthetic Communications, 1996 , vol. 26, # 6 p. 1233 - 1245
反应条件
1: 18-crown-6 / acetonitrile / 24 h / Heating 2: conc aq. HCl View Scheme
参考文献
Hayashi, Masatoshi; Wada, Kojiro; Munakata, Katsura
Agricultural and Biological Chemistry, 1983 , vol. 47, # 11 p. 2653 - 2656
反应条件
1: methanolic-aqueous KOH-solution 2: KOH-solution View Scheme
参考文献
Perkin; Ray; Robinson
Journal of the Chemical Society, 1926 , p. 943,946
Journal of the Chemical Society, 1927 , p. 2095,2098
反应条件
water; potassium carbonate
参考文献
Chen et al.
Huaxue Xuebao, 1956 , vol. 22, p. 455,457
Chem.Abstr., 1958 , p. 11029
参考文献
Bachman; Levine
Journal of the American Chemical Society, 1948 , vol. 70, p. 599
