4-羟基-3-甲基苯甲酸合成路线 （共 31 条）
反应条件
sulfuric acid in methanol 48 h; Heating / reflux;
参考文献
PFIZER LIMITED; PFIZER INC.
Patent: WO2005/82866 A2, 2005 ;
Location in patent: Page/Page column 64-65 ;
WO 2005/082866 A2
参考文献
Pfister
Journal of the American Chemical Society, 1921 , vol. 43, p. 375
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Pfister
Privatmitteilung
参考文献
Pfister
Journal of the American Chemical Society, 1921 , vol. 43, p. 375
Full Text View citing articles Show Details
Pfister
Privatmitteilung
反应条件
potassium carbonate 16 h; Reflux;
参考文献
Galemmo, JR., Robert; Holland, Richard; Hum, Gabriel; Pajouhesh, Hossein; Chahal, Navjot; Seid-Bagherzadeh, Mehran; Girard, Amy
Patent: US2009/270394 A1, 2009 ;
Location in patent: Page/Page column 10-11 ;
US 20090270394 A1
反应条件
1: glacial acetic acid; bromine 2: lime/chalk/ / 300 °C View Scheme
参考文献
Robertson
Journal of the Chemical Society, 1908 , vol. 93, p. 789
反应条件
hydrogenchloride T=180 - 185°C; im geschlossenem Rohr;
参考文献
Remsen; Iles
American Chemical Journal, 1879 , vol. 1, p. 122
反应条件
T=180 - 185°C; im geschlossenen Rohr;
参考文献
Remsen; Iles
American Chemical Journal, 1879 , vol. 1, p. 122
反应条件
bei der Destillation;
参考文献
Remsen; Iles
American Chemical Journal, 1879 , vol. 1, p. 122
参考文献
Kikuchi
Yakugaku Zasshi, 1958 , vol. 78, p. 576,579
Chem.Abstr., 1958 , p. 18492
