2,2-二甲基-2,3-二氢-1-苯并呋喃-7-羰酰氯合成路线 （共 6 条）
反应条件
1: 90percent HCOOH / 3 h / Heating
2: NaOH / H2O / 3 h / Heating
3: SOCl2 / 3 h / Heating
View Scheme
参考文献
Robertson, David W.; Lacefield, William B.; Bloomquist, William; Pfeifer, William; Simon, Richard L.; Cohen, Marlene L.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 2 p. 310 - 319
反应条件
1: N-methylpyrrolidinone / 7 h / Heating
2: 90percent HCOOH / 3 h / Heating
3: NaOH / H2O / 3 h / Heating
4: SOCl2 / 3 h / Heating
View Scheme
参考文献
Robertson, David W.; Lacefield, William B.; Bloomquist, William; Pfeifer, William; Simon, Richard L.; Cohen, Marlene L.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 2 p. 310 - 319
反应条件
1: NaOH / H2O / 3 h / Heating
2: SOCl2 / 3 h / Heating
View Scheme
参考文献
Robertson, David W.; Lacefield, William B.; Bloomquist, William; Pfeifer, William; Simon, Richard L.; Cohen, Marlene L.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 2 p. 310 - 319
反应条件
1: HCl (gas) / Heating
2: K2CO3 / acetone / Heating
3: N-methylpyrrolidinone / 7 h / Heating
4: 90percent HCOOH / 3 h / Heating
5: NaOH / H2O / 3 h / Heating
6: SOCl2 / 3 h / Heating
View Scheme
参考文献
Robertson, David W.; Lacefield, William B.; Bloomquist, William; Pfeifer, William; Simon, Richard L.; Cohen, Marlene L.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 2 p. 310 - 319
反应条件
1: K2CO3 / acetone / Heating
2: N-methylpyrrolidinone / 7 h / Heating
3: 90percent HCOOH / 3 h / Heating
4: NaOH / H2O / 3 h / Heating
5: SOCl2 / 3 h / Heating
View Scheme
参考文献
Robertson, David W.; Lacefield, William B.; Bloomquist, William; Pfeifer, William; Simon, Richard L.; Cohen, Marlene L.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 2 p. 310 - 319
反应条件
thionyl chloride in toluene
3 h; Heating;
参考文献
Stanetty; Koller; Purstinger; Grubner
Archiv der Pharmazie, 1993 , vol. 326, # 6 p. 351 - 358
