Stewart, Scott G.; Spagnolo, Daniel; Polomska, Marta E.; Sin, Melvin; Karimi, Mahdad; Abraham, Lawrence J.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 21 p. 5819 - 5824
1: With pyridine T=20 - 85°C; 6 h; 2: With 1,1'-carbonyldiimidazole T=40°C; 2 h; 3: With hydrogenchloride in ethanol; water T=5 - 25°C; pH=7; 4 h; Product distribution / selectivity;
1: With pyridine T=10 - 15°C; 4 h; 2: With 1,1'-carbonyldiimidazole T=20°C; 4 h; 3: With hydrogenchloride in water T=5 - 20°C; pH=7; 4 h; Product distribution / selectivity;
4-(N,N-dimethlyamino)pyridine; 1,1'-carbonyldiimidazole in tetrahydrofuran 16 h; RefluxInert atmosphere;
参考文献
Muller, George W.; Konnecke, William E.; Smith, Alison M.; Khetani, Vikram D.
Organic Process Research and Development, 1999 , vol. 3, # 2 p. 139 - 140
