5-氨基-2-羟基苯乙酮合成路线 (共 14 条)
反应条件
in tetrahydrofuran T=60°C; 0.333333 h; Yield given;
参考文献
Cushman, Mark; Zhu, Helen; Geahlen, Robert L.; Kraker, Alan J.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 20 p. 3353 - 3362
反应条件
1: With sulfuric acid; sodium nitrite in water
0.583333 h;
2: With sulfuric acid; copper; potassium iodide in water
T=20 - 65°C;
参考文献
ROWETT RESEARCH INSTITUTE
Patent: WO2004/7475 A1, 2004 ;
Location in patent: Page 74-75 ;
反应条件
pyrrolidine in ethanol
Reflux;
参考文献
Shinde, Pundlik; Srivastava, Sanjay K.; Odedara, Rajendra; Tuli, Davinder; Munshi, Siralee; Patel, Jitendra; Zambad, Shitalkumar P.; Sonawane, Rajesh; Gupta, Ramesh C.; Chauthaiwale, Vijay; Dutt, Chaitanya
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 3 p. 949 - 953
反应条件
pyridine in dichloromethane
参考文献
Elliott; Selnick; Claremon; Baldwin; Buhrow; Butcher; Habecker; King; Lynch Jr.; Phillips; Ponticello; Radzilowski; Remy; Stein; White; Young
Journal of Medicinal Chemistry, 1992 , vol. 35, # 21 p. 3973 - 3976