2,4-二氯苯甲酸合成路线

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Gaidukevich, A. N.; Levitin, E. Ya.; Kravchenko, A. A.; Kazakov, G. P.; Mikitenko, E. E.; et al.
Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 3 p. 180 - 182
Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 3 p. 165 - 168

50-84-02,4-二氯苯甲酸+

536-90-3间氨基苯甲醚

91-37-2

参考文献

Gaidukevich, A. N.; Levitin, E. Ya.; Kravchenko, A. A.; Kazakov, G. P.; Mikitenko, E. E.; et al.
Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 3 p. 180 - 182
Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 3 p. 165 - 168

50-84-02,4-二氯苯甲酸+

27191-09-9间苯胺氢氟乙酰氯

91-37-2

参考文献

Ackerman; Haldorsen; Tendick; Elslager
Journal of medicinal chemistry, 1968 , vol. 11, # 2 p. 315 - 321

50-84-02,4-二氯苯甲酸+

104-94-9对甲氧基苯胺

91-38-34-氯-2-(4-甲氧基苯胺基)-苯甲酸

参考文献

Mei, Xuefeng; August, Adam T.; Wolf, Christian
Journal of Organic Chemistry, 2006 , vol. 71, # 1 p. 142 - 149

50-84-02,4-二氯苯甲酸

94355-79-0

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Kitchen, S. E.; Wang, Yueh-Hwa; Baumstark, A. L.; Wilson, W. D.; Boykin, D. W.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 940 - 944

50-84-02,4-二氯苯甲酸+

106-49-0对甲苯胺

94355-79-0

参考文献

Johns, Stephen C.; Crouch, Laurie L.E.; Grieve, Stephen; Maloney, Holly L.; Peczkowski, Gary R.; Jones, Allison E.; Sharp, Duncan; Smith, Robert B.
Tetrahedron Letters, 2014 , vol. 55, # 22 p. 3308 - 3311

50-84-02,4-二氯苯甲酸

95112-15-5

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Khalifa, Latifa; Rosales, Maria-Jose; Mascaro, Carmen; Karolak-Wojciechowska, Janina; Bsiri, Nadia; Brouant, Pierre; Barbe, Jacques
Arzneimittel-Forschung/Drug Research, 2000 , vol. 50, # 2 p. 163 - 166

99282-79-82-羧基甲基氨基-4-氯苯甲酸

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Fuji Chemical Industry Co., Ltd.; Fujisawa Pharmaceutical Co., Ltd.
Patent: US6201121 B1, 2001 ;

50-84-02,4-二氯苯甲酸+

56-40-6甘氨酸

99282-79-82-羧基甲基氨基-4-氯苯甲酸

参考文献

Docampo, Maite L.; Pellon, Rolando F.; Estevez-Braun, Ana; Ravelo, Angel G.
European Journal of Organic Chemistry, 2007 , # 24 p. 4111 - 4115

50-84-02,4-二氯苯甲酸+

12775-96-1+

56-40-6甘氨酸

99282-79-82-羧基甲基氨基-4-氯苯甲酸

参考文献

Hoechst Aktiengesellschaft
Patent: US5821385 A1, 1998 ;