5-庚基苯-1,3-二醇合成路线 （共 36 条）
反应条件
1: 72 percent / diethyl ether / 2 h / Heating 2: 73 percent / trifluoroacetic acid; hydrogen / Pd/C / ethanol / 168 h / 2585.74 Torr 3: 100 percent / BBr3 / CH2Cl2 / 0 - 25 °C View Scheme
参考文献
Huffman, John W.; Liddle, John; Duncan Jr., Sammy G.; Yu, Shu; Martin, Billy R.; Wiley, Jenny L.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 12 p. 2383 - 2396
反应条件
1: 72 percent / diethyl ether / 2 h / Heating 2: 73 percent / trifluoroacetic acid; hydrogen / Pd/C / ethanol / 168 h / 2585.74 Torr 3: 100 percent / BBr3 / CH2Cl2 / 0 - 25 °C View Scheme
参考文献
Arisawa; Ohmura; Kobayashi; Morita
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 9 p. 2431 - 2434
反应条件
hydrogenchloride in water T=90°C; 12 h;
参考文献
Bunyapaiboonsri, Taridaporn; Yoiprommarat, Seangaroon; Khonsanit, Artit; Komwijit, Somjit
Journal of Natural Products, 2008 , vol. 71, # 5 p. 891 - 894
反应条件
hydrogenchloride in water T=90°C; 12 h;
参考文献
Bunyapaiboonsri, Taridaporn; Yoiprommarat, Seangaroon; Khonsanit, Artit; Komwijit, Somjit
Journal of Natural Products, 2008 , vol. 71, # 5 p. 891 - 894
参考文献
Harris,T.M.; Carney,R.L.
Journal of the American Chemical Society, 1967 , vol. 89, p. 6734 - 6741
反应条件
1: 41 percent / tetrahydrofuran / -20 - 20 °C 2: 82 percent / 2N KOH / 2 h / Heating 3: 44 percent / Et3SiH / trifluoroacetic acid / 24 h / 45 °C 4: 32 percent / BBr3 / CH2Cl2 / -20 - 20 °C View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
sodium hydroxide in water Heating;
参考文献
Kato,T.; Hozumi,T.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, p. 1574 - 1578
反应条件
1: NaH 2: NaOH / H2O / Heating View Scheme
参考文献
Kato,T.; Hozumi,T.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, p. 1574 - 1578
反应条件
sodium T=150 - 180°C; Verschmelzen des Reaktionsprodukts mit KOH bei 250grad;
参考文献
Asahina; Hashimoto
Chemische Berichte, 1934 , vol. 67, p. 416,419
Yakugaku Zasshi, 1935 , vol. 55, p. 504,510
反应条件
1: 52 percent / lithium chips / 0.75 h 2: boron tribromide, pyridine hydrochloride / CH2Cl2 / 24 h / -78 °C View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
