N-羟基-2,4-二甲氧基-苯甲酰胺合成路线 (共 1 条)
反应条件
1: With hydroxylamine hydrochloride; potassium carbonate in ethanol
T=85°C; 27 h;
2: With hydrogenchloride in ethanol; water
Acidic conditions;
3: With sodium hydroxide in water
Alkaline aqueous solution;
参考文献
ACTELION PHARMACEUTICALS LTD.
Patent: US2008/318955 A1, 2008 ;
Location in patent: Page/Page column 12 ;
US 20080318955 A1